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TranscriptomicsTranscription profiling of mouse 344SQ lung adenocarcinoma cells under forced miR-200 expression
Metastatic disease is a primary cause of cancer-related death, and factors governing tumor cell metastasis have not been fully elucidated. Here we addressed this question by using tumor cell lines derived from mice that develop metastatic lung adenocarcinoma owing to expression of mutant K-ras and p...
ORGANISM(S): Mus musculus 
2009-11-28 | E-GEOD-15741 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse 344SQ lung adenocarcinoma cells with high metastatic potential (syngeneic mouse model)
The biologic basis for NSCLC metastasis is not well understood. Here we addressed this deficiency by transcriptionally profiling tumors from a genetic mouse model of human lung adenocarcinoma that develops metastatic disease owing to the expression of K-rasG12D and p53R172H. As a tool to investigate...
ORGANISM(S): Mus musculus 
2009-11-28 | E-GEOD-14458 | biostudies-arrayexpress
ProteomicsThe Cancer Cell Target Discovery. Comparing Laboratory Evolution of Expanded DNA Six-Nucleotide Alphabets with Standard Four-Nucleotide Alphabets
Artificial evolvable genetic information systems (AEGIS) are DNA-like molecules that can be copied, support laboratory in vitro evolution (LIVE), and evolve to give AegisBodies, analogs of antibodies. However, unlike DNA aptamers built from four different nucleotides, AegisBodies are built from si...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055115 | Pride
Target determination Aptamer Molecular interactions Cancer cell Unnatural bases 
ProteomicsThe Cancer Cell Target Discovery. Comparing Laboratory Evolution of Expanded DNA Six-Nucleotide Alphabets with Standard Four-Nucleotide Alphabets
Artificial evolvable genetic information systems (AEGIS) are DNA-like molecules that can be copied, support laboratory in vitro evolution (LIVE), and evolve to give AegisBodies, analogs of antibodies. However, unlike DNA aptamers built from four different nucleotides, AegisBodies are built from si...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055130 | Pride
Target determination Aptamer Molecular interactions Cancer cell Unnatural bases 
ProteomicsThe Cancer Cell Target Discovery. Comparing Laboratory Evolution of Expanded DNA Six-Nucleotide Alphabets with Standard Four-Nucleotide Alphabets
Artificial evolvable genetic information systems (AEGIS) are DNA-like molecules that can be copied, support laboratory in vitro evolution (LIVE), and evolve to give AegisBodies, analogs of antibodies. However, unlike DNA aptamers built from four different nucleotides, AegisBodies are built from si...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055107 | Pride
Target determination Aptamer Molecular interactions Cancer cell Unnatural bases 
Unknown[Historical Versions Pending Deletion] Multiscale brain-wide mapping of α-synuclein-driven dopaminergic degeneration and white matter impairment in α-synucleinopathy mice
Not available
S-BIAD3402 | bioimages
Proteomicsproteomic analysis in cataract of Ailuropoda melanoleuca (Giant panda)
proteomic analysis between cataract of Ailuropoda melanoleuca (Giant panda) and normal panda
ORGANISM(S): Ailuropoda Melanoleuca 
2022-01-18 | PXD031039 |
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