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Recent studies have revealed that long non-coding RNAs (lncRNAs) participate in all steps of cancer initiation and progression by regulating protein coding genes at the epigenetic, transcriptional and post-transcriptional levels. LncRNAs are in turn regulated by other genes, forming a complex regula...
ORGANISM(S): Homo sapiens 
Pediatric acute lymphoblastic leukemia (ALL) contains cytogenetically distinct subtypes that respond differently to cytotoxic drugs. Subtype classification can be also achieved through gene expression profiling. However, how to apply such classifiers to a single patient and correctly diagnose the di...
ORGANISM(S): Homo sapiens 
Background Aging is characterized by the gradual loss of physiological integrity, resulting in impaired function and easier death. This deterioration is a major risk factor for major human pathological diseases, including cancer, diabetes, cardiovascular disease and neurodegenerative diseases. It is...
ORGANISM(S): Homo Sapiens 
2022-05-05 | PXD033660 |
To study the mechanism underlying IDA-induced anti-tumor activity for Abi resistance, LNCaP-Abi cells were treated with Abi alone and in combination with IDA for 24 h. Protein profiles were determined by mass spectrometry
ORGANISM(S): Homo Sapiens 
2022-01-12 | PXD030905 |
After ectopic expression of Flag-USP38 or an empty vector in HEK293T cells for 48 hours, cells were lysed, and the supernatant after lysis was added to magnetic beads coupled with Flag antibodies. The mixture was incubated at 4°C overnight for pull-down. Subsequently, the magnetic beads were washed ...
ORGANISM(S): Homo Sapiens 
2024-08-26 | PXD055320 |
Chemoresistance remains to be the major restriction on the clinical use of cisplatin. Aberrant changes in protein glycosylation are closely associated with the growth, invasion, metastasis, and resistance to chemotherapy of cancer cells. Comprehensive study on the role of protein glycosylation in th...
ORGANISM(S): Homo Sapiens 
2021-09-18 | PXD028691 |
The interaction proteins were obtained by immunoprecipitation (IP) of VWA8 using retinal pigment epithelium cell lysate.
ORGANISM(S): Homo Sapiens 
2026-03-29 | PXD076332 |
Phosphorylation sites identified at the C-terminus of mGlu5 by mass spectrometry analysis
ORGANISM(S): Homo Sapiens 
2026-04-01 | PXD076479 |
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