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TranscriptomicsTranscription profiling of Arabidopsis pollen germination and tube growth
Pollen germination, along with pollen tube growth, is an essential process for the reproduction of flowering plants. The germinating pollen with tip-growth characteristics provides an ideal model system for the study of cell growth and morphogenesis. As an essential step towards a detailed underst...
ORGANISM(S): Arabidopsis thaliana 
2008-10-25 | E-GEOD-6696 | biostudies-arrayexpress
TranscriptomicsDifferentiation of human embryonic stem cells towards hepatocytes
To understand in detail the molecular phases that occur during the differentiation of human embryonic stem cells to hepatocyte-like cells we performed an RNA-seq time course of the stages of differentiation across the 21 day differentiation time course. We used a chemically defined (serum-free) prot...
ORGANISM(S): Homo sapiens 
2017-04-28 | E-GEOD-70741 | biostudies-arrayexpress
UnknownResponse Patterns and Mechanisms of Seed Germination and Mortality of Common Plants in Subalpine Wet Meadows to In Situ Burial.
Not available
S-EPMC12525858 | biostudies-literature
TranscriptomicsDeep sequencing identify tissue-specific microRNAs and their target genes involved in tanshinones biosynthesis in Salvia miltiorrhiza
Salvia miltiorrhiza is one of the most popular traditional medicinal herbs in Asian nations. Its dried root contains a number of tanshinones, protocatechuic aldehyde, salvianolic acid B and rosmarinic, and is used for the treatment of various diseases. To make clear the molecular mechanism of tanshi...
ORGANISM(S): Salvia miltiorrhiza 
2015-03-01 | E-GEOD-60757 | biostudies-arrayexpress
MetabolomicsMetabolomic analysis of alfalfa (Medicago sativa L.) root-symbiotic rhizobia responses under alkali stress
Alkaline salts (e.g., NaHCO3 and Na2CO3) causes more severe morphological and physiological damage to plants than neutral salts (e.g., NaCl and Na2SO4) due to differences in pH. The mechanism by which plants respond to alkali stress is not fully understood, especially in plants having symbotic relat...
2018-07-27 | MTBLS481 | MetaboLights
ProteomicsInvestigation on the quantitative proteomic responses of bloom-forming Cyanobacteria Microcystis aeruginosa to phosphorus depletion and starvation by the method of isobaric tags for relative and absolute quantitation (iTRAQ)
Microcystis aeruginosa cells were treated with phosphorus repletion, depletion and starvation. Isobaric tags for relative and absolute quantitation (iTRAQ) proteomic method was employed to explore to the effects of phosphorus limitation on Microcystis aeruginosa cells at the protein level. This inve...
ORGANISM(S): Microcystis aeruginosa 
2021-06-29 | PXD025188 | Pride
Microcystis aeruginosa Phosphorus Itraq 
UnknownPhase II trial of cetuximab with or without paclitaxel in patients with advanced urothelial tract carcinoma.
Not available
S-EPMC3454772 | biostudies-literature
TranscriptomicsExpression profiling of MDA-MB-231 breast cancer cells treated with DOT1L inhibitors and siDOT1L
MDA-MB-231 cell line with relatively high DOT1L levels was treated with two potent, selective inhibitors of the DOT1L histone methyl transferase. These compounds can inhibit cells migration and invasion and induce differentiation. Here we provide expression profiling data of cells treated with two D...
ORGANISM(S): Homo sapiens 
2015-02-18 | E-GEOD-56630 | biostudies-arrayexpress
ProteomicsMass spectrometry-based direct detection of multiple types of protein thiol modifications in pancreatic beta cells under endoplasmic reticulum stress
A 2D-LC-MS/MS strategy coupled with TMT-10 labeling was applied to mouse pancreatic beta cells (hetaTC-6) induced with ER stress by Thapsigargin to study the global proteome and protein cysteine PTM changes under ER stress. Samples were digested with trypsin, labeled with 10-plex TMT, then analyzed ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-05-29 | MSV000087543 | MassIVE
UnknownThe mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysis.
Not available
S-EPMC2929599 | biostudies-literature
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