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GenomicsTranscription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells [EBF1]
Transcription factor Ebf1 is an important determinant of early B lymphopoiesis. To gain insight into differentiation stage-specific functions of Ebf1, we conditionally inactivated Ebf1. We found that Ebf1 is required for proliferation, survival and signaling of pro-B cells and peripheral B cell su...
ORGANISM(S): Mus musculus 
2012-04-02 | E-GEOD-35910 | biostudies-arrayexpress
UnknownSAR by interligand nuclear overhauser effects (ILOEs) based discovery of acylsulfonamide compounds active against Bcl-x(L) and Mcl-1.
Not available
S-EPMC3165075 | biostudies-literature
UnknownTRAF4-mediated ubiquitination-dependent activation of JNK/Bcl-xL drives radioresistance.
Not available
S-EPMC9918491 | biostudies-literature
UnknownAnti-apoptotic protein BCL-XL as a therapeutic vulnerability in gastric cancer.
Not available
S-EPMC10272913 | biostudies-literature
UnknownSynthesis and evaluation of Apogossypol atropisomers as potential Bcl-xL antagonists.
Not available
S-EPMC2653056 | biostudies-literature
GenomicsTranscription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells
This SuperSeries is composed of the following subset Series: GSE35910: Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferative expansion and survival of B cells [EBF1] GSE35914: Transcription factor Ebf1 regulates differentiation stage-specific signaling, prolifer...
ORGANISM(S): Mus musculus 
2012-04-02 | E-GEOD-35915 | biostudies-arrayexpress
ProteomicsIntact extracellular vesicle cross-linking on vesicles derived from MDA-MB-231 and LM2 cells
The development of any pharmaceutical requires characterization of the compound, usually be several techniques. Therefore, characterizing the protein content and biochemical state of EVs is of great importance for their useif they are to be used as biopharmaceuticals. Structural characterization of ...
ORGANISM(S): Homo sapiens (Human) 
2022-11-08 | PXD029591 | Pride
Tnbc Evs Xl-ms Structural proteomics Cx-ms 
UnknownAssociation Between 3 IL-10 Gene Polymorphisms and Cardiovascular Disease Risk: Systematic Review With Meta-Analysis and Trial Sequential Analysis.
Not available
S-EPMC4753955 | biostudies-literature
UnknownInvestigation of Asian Dyes and Pigments from the Artifact of "Murongzhi" and the Silk Road in China.
Not available
S-EPMC9850485 | biostudies-literature
UnknownStructural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis.
Not available
S-EPMC8052441 | biostudies-literature
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