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TranscriptomicsExpression changes in Tetrahymena thermophila TRX1 and EZL2 gene knockouts and after hydroxyurea (HU) treatment
12 genome-wide microarrays to investigate the Tetrahymena thermophila gene expression changes in TRX1 and EZL2 gene knockout and hydroxyurea (HU) treatment conditions. For the TRR1 knockout (KO) condition, wild type (WT427) cells and TRX1 KO cells were cultured using 1XSPP, 30 degrees, 100 rpm shaki...
ORGANISM(S): Tetrahymena thermophila 
2013-09-04 | E-GEOD-44990 | biostudies-arrayexpress
ProteomicsModified Sanjia Powder Ameliorates Cognitive Impairment and Exerts Neuroprotective Effects in 5×FAD Mice: Insights from Quantitative Proteomics
Proteomics reveals Sanjia neuroprotection mechanisms
ORGANISM(S): Mus Musculus 
2025-12-26 | PXD072435 |
ProteomicsProteome profiling of lung tissues in chronic obstructive pulmonary disease (COPD): disfunction of platelet and macrophage contribute to pathogenesis of COPD
Chronic obstructive pulmonary disease (COPD) is a worldwide public health challenge because of its high prevalence and related disability and mortality; however, the pathogenesis of COPD remains unknown. The aim of this study was to reveal the critical proteins involved in the pathogenesis of COPD. ...
ORGANISM(S): Homo Sapiens 
2020-01-17 | PXD017158 |
ProteomicsHippocampal subfields proteome analysis and comparation in Alzheimer’s disease providing new sight on glia function
The hippocampus and entorhinal cortex are the earliest areas affected by AD pathology, which are related to early memory loss in patients. The hippocampus subfields are heterogeneous, with different order and degree affect by AD pathology. Studying the molecular changes may explain the difference, a...
ORGANISM(S): Homo Sapiens 
2021-07-16 | PXD027380 |
MetabolomicsElevated temperature accelerates leaf senescence and promotes leaf nitrogen transport to improve rice grain protein synthesis
Elevated temperatures during grain filling severely constrain rice yield and quality. Although additional nitrogen can mitigate the adverse effects of elevated temperature, both factors increase grain protein content, and the underlying physiological mechanisms remain poorly understood. Here, we con...
2026-06-17 | MTBLS14777 | MetaboLights
ProteomicsPP2Acα regulates cerebellar development via phosphorylation-dependent neuronal programs
The proteomics and phosphorylation proteomics of PP2Acα regulates cerebellar development via phosphorylation-dependent neuronal programs.
ORGANISM(S): Mus Musculus 
2025-11-28 | PXD071414 |
ProteomicsThe data of protein expression of hMSCs in Soft, Medium and Stiff group
After treated with different stiffness and macrophage paracrine signals at the same stiffness for 3 days, MSCs were harvested for proteomic analysis. The label-free quantification (LFQ) based proteomic analysis was performed for global protein expressions.
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD035511 |
ProteomicsTRIM28 is an E3 ligase of IRP2 suppressing ischemia/reperfusion-induced myocardial ferroptosis
Myocardial ischemia/reperfusion (I/R) injury is a common and severe clinical complication in patients with ischemic heart disease (IHD) after reperfusion therapy. Effective therapeutic strategies for myocardial I/R injury remain limited. Ferroptosis is a form of regulated cell death characterized by...
ORGANISM(S): Rattus Norvegicus 
2025-12-28 | PXD072478 |
ProteomicsIntegrated Landscape of Plasma Metabolism and Proteome for Post-traumatic Deep Vein Thrombosisasma Metabolism and Proteome for Post-traumatic Deep Vein Thrombosis
Deep vein thrombosis (DVT) is a leading cause of morbidity and mortality after trauma. Here, we integrate metabolomics and proteomics in up to 680 individuals with and without DVT after trauma (pt-DVT) to reveal the metabolic alterations and their function, and provide potential biomarkers. We carri...
ORGANISM(S): Homo Sapiens 
2024-07-22 | PXD054131 |
ProteomicsTandem proteomic and N-glycoproteomic analysis of extracellular vesicles
Extracellular vesicles (EVs) derived from diverse biofluids have emerged as promising noninvasive diagnostic biomarkers or signatures for various diseases. EV-associated N-glycoproteins are crucial for the biological functions of EVs and hold significant potential for disease diagnosis and prognosis...
ORGANISM(S): Homo Sapiens 
2024-11-05 | PXD057512 |
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