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UnknownPpMYC2 and PpJAM2/3 antagonistically regulate lignin synthesis to cope with the disease in peach fruit.
Not available
S-EPMC12392935 | biostudies-literature
UnknownSOFAR: Large-Scale Association Network Learning.
Not available
S-EPMC7970712 | biostudies-literature
MetabolomicsThe Inhibition of B7H3 by 2-HG Accumulation Is Associated With Downregulation of VEGFA in IDH Mutated Gliomas
B7H3 (also known as CD276) is a co-stimulator checkpoint protein of the cell surface B7 superfamily. Recently, the function beyond immune regulation of B7H3 has been widely studied. However, the expression preference and the regulation mechanism underlying B7H3 in different subtypes of gliomas is ra...
2021-05-26 | MTBLS2692 | MetaboLights
MetabolomicsMechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis

Zhuyu pill (ZYP) is a traditional Chinese medicine prescription composed of two drugs, Coptis chinensis Franch. and Tetradium ruticarpum (A. Jussieu) T. G. Hartley, and is commonly used in the clinical treatment of diseases of the digestive system. However, the mechanism underly...

2022-11-02 | MTBLS4980 | MetaboLights
MetabolomicsElevated temperature accelerates leaf senescence and promotes leaf nitrogen transport to improve rice grain protein synthesis
Elevated temperatures during grain filling severely constrain rice yield and quality. Although additional nitrogen can mitigate the adverse effects of elevated temperature, both factors increase grain protein content, and the underlying physiological mechanisms remain poorly understood. Here, we con...
2026-06-17 | MTBLS14777 | MetaboLights
ProteomicsGlycoPCT: quantitative glycoproteomics based on pressure cycling technology reveals distinctive N-glycosylation in human liver with non-alcoholic fatty liver disease
Protein N-glycosylation plays a crucial role in the human liver, impacting key functions like hepatocyte lipid metabolism hepatocyte apoptosis, and inflammatory response. Despite its significance, the site-specific N-glycosylation patterns and their variations of liver biosy samples between healthy ...
ORGANISM(S): Homo Sapiens 
PXD053626 |
ProteomicsAsymmetric dimethylarginine proteome of pancreatic ductal adenocarcinoma.
Protein arginine methylation has been established an essential protein modification regulating cancer initiation and progression, but its implications in PDAC (Pancreatic ductal adenocarcinoma) still remains poorly elucidated. In this study, we characterized ADMA (asymmetric dimethylarginine)-bearin...
ORGANISM(S): Homo Sapiens 
2020-02-18 | PXD017577 |
ProteomicsHSGA glioma tissue and benign tissue in Huashan Hospital
HSGA glioma tissue and benign tissue in Huashan Hospital
ORGANISM(S): Homo Sapiens 
PXD056311 |
ProteomicsIntegrative Proteogenomic Characterization Reveals Therapeutic Targets in Poorly Differentiated and Anaplastic Thyroid Cancers
In our study, we constructed a multicenter thyroid-cancer cohort consisting of 467 formalin-fixed paraffin-embedded (FFPE) samples, among which WES, proteome, and phosphorylated proteome analysis were conducted. Thyroid tumors consisted of 124 ATC samples, 47 PDTC samples and 177 PTC samples (includ...
ORGANISM(S): Homo Sapiens 
2025-03-16 | PXD054521 |
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