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UnknownA pragmatic randomized controlled trial to evaluate the efficacy and safety of an oral short-course regimen including bedaquiline for the treatment of patients with multidrug-resistant tuberculosis in China: study protocol for PROSPECT.
Not available
S-EPMC10986125 | biostudies-literature
ProteomicsAntibacterial and Anti-virulence Activity of the Repurposed Agent SX-682 Against Staphylococcus aureus
Proteomics of Staphylococcus aureus SA113 after treatment with SX - 682
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Nctc 8325 
2025-12-31 | PXD072538 |
ProteomicsDifferential proteomics analysis on plasma from anlotinib-treated advanced non-small cell lung cancer patients
Anlotinib has been demonstrated to be effective in advanced non-small cell lung cancer (NSCLC) patients. DNA-seq- and RNA-seq-based anlotinib molecular mechanism and biomarker screening have been introduced in previous studies. The underlying value of proteomics for anlotinib study is still unclear....
ORGANISM(S): Homo Sapiens 
2020-03-05 | PXD017919 |
ProteomicsMetabolic regulation of cytoskeleton functions by HDAC6-catalyzed α-tubulin lactylation
Metabolic regulation of cytoskeleton functions by HDAC6-catalyzed α-tubulin lactylation
ORGANISM(S): Mus Musculus 
2024-09-12 | PXD055797 |
ProteomicsProteomic analysis of the four rat models of depression
Major depressive disorder (MDD) is a highly heterogeneous psychiatric disorder. The pathogenesis of MDD remained unclear, and it may be associated with exposure to different stressors. Most previous studies have focused on molecular changes in a single stress-induced depression model, which limited ...
ORGANISM(S): Rattus Norvegicus 
2023-05-22 | PXD043285 |
ProteomicsInsight of novel biomarkers for papillary thyroid carcinoma through multi-omics
Our multi-omics analysis of local patients demonstrated significant distinctions compared to TCGA-THCA cohorts, highlighting the unique genetic characteristics of Chinese individuals with PTC. We identified novel biomarkers that hold potential for diagnosis and prognosis of PTC. Furthermore, develop...
ORGANISM(S): Homo Sapiens 
2023-08-23 | PXD044815 |
ProteomicsPD-L1 Mediated Immune Evasion in Triple Negative Breast Cancer Is Linked to the Loss of ZNF652
The intrinsic regulation of PD-L1 expression remains unclear. Here we report that ZNF652 is a potent transcription repressor of PD-L1. ZNF652 frequently loses heterozygosity (LOH) in various cancers. Higher LOH rate and lack of estrogen-inducible transcription lead to suppressed expression of ZNF652...
ORGANISM(S): Homo Sapiens 
2023-09-29 | PXD045945 |
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