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ProteomicsTreachery of hepatic protector triggers Notch signaling to promote hepatocyte-originated cholangiocarcinoma
Here, we found mesencephalic astrocyte-derived neurotrophic factor (MANF), a hepatic protector, was upregulated in human ICC tissues and sleeping beauty transposon (SBT) or thioacetamide (TAA)-induced mice ICC tissues. We verified the oncogenic role of MANF in ICC using cell lines overexpressing/kno...
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD048451 | Pride
Hepatocytes Ip-ms Hucct1 Notch Cholangiocarcinoma Ck19 
UnknownEfficacy and Tolerability of First-Line Cetuximab Plus Leucovorin, Fluorouracil, and Oxaliplatin (FOLFOX-4) Versus FOLFOX-4 in Patients With RAS Wild-Type Metastatic Colorectal Cancer: The Open-Label, Randomized, Phase III TAILOR Trial.
Not available
S-EPMC6324088 | biostudies-literature
ProteomicsProteomic study of exfoliation syndrome
We provided a comprehensive plasma proteome analysis and expanded the profile of human plasma proteome. The differential plasma proteomic analysis of age-related cataract and exfoliation syndrome with/without glaucoma indicated that plasma proteome can reflect the pathophysiological situation of dis...
ORGANISM(S): Homo Sapiens 
2025-03-17 | PXD061945 |
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