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CpG island methylation profiling of human cholangiocarcinoma, ECC and ICC, cases compared to matched normal controls or to pools of corresponding normal controls. Goal was to identify cholangiocarcinoma-specific differentially methylated regions (DMRs). Highly methylated DNA from cases and controls ...
ORGANISM(S): Homo sapiens 
Using MCIp, we enriched highly methylated DNA from a normal mucosa control and from three OPSCC patient subgroups regarding the HPV status: group A, DNA-RNA- (Tu1-Tu5); group B, DNA+RNA- (Tu6-Tu10); group C, DNA+RNA+ (Tu11-Tu15). 3 groups of tumor biopsies, 5 samples each regarding HPV status: DNA-R...
ORGANISM(S): Homo sapiens 
HSC73_clone: Bone marrow mononuclear cells from the healthy 73 years old female were thawed and labeled with Alexa-Fluor 488-conjugated anti-CD34 (581, Biolegend), Alexa-Fluor 700-conjugated anti-CD38 (HIT2, eBioscience), a cocktail of APC-conjugated lineage antibodies consisting of anti-CD4 (RPA-T4...
BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma (PDAC) is usually incurable. Contrary to genetic mechanisms involved in PDAC pathogenesis, epigenetic alterations are ill defined. Here we determine the contribution of epigenetically silenced genes to the development of PDAC. METHODS: We invest...
ORGANISM(S): Homo sapiens 
Investigation of the upregulation of lncRNA genes in 13q14.3 and ist correlation with downregulation in cis of a gene cluster regulating NF-kB
ORGANISM(S): Homo sapiens 
RNA sequencing data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
ChIPseq data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
WGBS data of whole blood samples from smoking and non-smoking mothers and their children at gestation/birth and follow-up years.
Whole-blood samples of 16 mother-child pairs with differing maternal smoking behaviour were bisulfite treated and sequenced with deep coverage to identify smoking-associated differentially methylated regions. RNA-sequencing and ChIP-sequencing of 4 chromatin marks complete the data set and allow for...
ICGC MMML-seq Data Freeze March 2013 transcriptome sequencing
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