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TranscriptomicsContribution of Veillonella parvula to Pseudomonas aeruginosa mediated pathogenicity in a murine tumor model system
We investigated the specific interactions of the most dominant bacterial CF-pathogen, Pseudomonas aeruginosa, and the anaerobic bacterium Veilllonella parvula, that has been recovered at comparable cell numbers in the respiratory tract of CF patients. We used our recently established in-vivo murine ...
ORGANISM(S): Veillonella parvula DSM 2008 
2014-11-06 | E-GEOD-58388 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Th cells expressing Foxp3 and UBD ectopically
Expression analysis revealed that UBD is a down-stream element of Foxp3 in human activated regulatory CD4+ T cells (Treg). Experiment Overall Design: Comparison of expression profiles measured in naturally occuring regulatory T-cells (Treg), Foxp3 and UBD transformed Th cells versus their controls w...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4527 | biostudies-arrayexpress
TranscriptomicsAroA deficient Salmonella Typhimurium – More than an auxotrophic mutant
Recombinant attenuated Salmonella are believed to act as powerful live vaccine carrier able to elicit protection against many infectious agents. ∆aroA exhibits auxotrophy for aromatic amino acids and is commonly used for attenuation. Interestingly, deletion of aroA dramatically increased virulence...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2016-08-09 | E-GEOD-74433 | biostudies-arrayexpress
TranscriptomicsEx vivo transcriptional profiling reveals a common set of genes important for the adaptation of Pseudomonas aeruginosa to chronically infected host sites
The opportunistic bacterium Pseudomonas aeruginosa is a major nosocomial pathogen causing both devastating acute and chronic persistent infections. During the course of an infection, P. aeruginosa rapidly adapts to the specific conditions within the host. In the present study, we aimed at the identi...
ORGANISM(S): Pseudomonas aeruginosa 
2012-11-14 | E-GEOD-25945 | biostudies-arrayexpress
TranscriptomicsIn-Vivo Expression Profiling of Pseudomonas aeruginosa Infections Reveals Niche-Specific and Strain-Independent Transcriptional Programs
Pseudomonas aeruginosa is a threatening, opportunistic pathogen causing disease in immunocompromised individuals. The hallmark of P. aeruginosa virulence is its multi-factorial and combinatorial nature. It renders such bacteria infectious for many organisms and it is often resistant to antibiotics. ...
ORGANISM(S): Pseudomonas aeruginosa 
2011-09-19 | E-GEOD-23007 | biostudies-arrayexpress
UnknownGene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells.
Not available
S-EPMC4580233 | biostudies-literature
UnknownRecent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Not available
S-EPMC3753504 | biostudies-literature
UnknownLongitudinal changes in peripapillary atrophy in the ocular hypertension treatment study: a case-control assessment.
Not available
S-EPMC4682350 | biostudies-literature
UnknownMEDULLOBLASTOMA
Not available
S-EPMC4046290 | biostudies-literature
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