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GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
UnknownPhase 1 Dose-Escalation Study of Pegylated Arginine Deiminase, Cisplatin, and Pemetrexed in Patients With Argininosuccinate Synthetase 1-Deficient Thoracic Cancers.
Not available
S-EPMC6141244 | biostudies-literature
UnknownA novel signature constructed by super-enhancer-related genes for the prediction of prognosis in hepatocellular carcinoma and associated with immune infiltration.
Not available
S-EPMC9948016 | biostudies-literature
ProteomicsProteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues
P4-ATPases are a subfamily of P-type ATPases that flip phospholipids across membranes to generate lipid asymmetry, a property vital to many cellular processes. Mutations in several P4-ATPases have been linked to severe neurodegenerative and metabolic disorders. Most P4-ATPases associate with one of...
ORGANISM(S): Mus musculus (Mouse) 
2018-07-20 | PXD009143 | Pride
Lc-ms/ms P4-atpases Affinity chromatography Tmem30a Phospholipid flippases Cdc50a Mouse tissues 
GenomicsNfatc1 Orchestrates Aging in Hair Follicle Stem Cells
Mouse hair follicles undergo synchronized cycles. Cyclical regeneration and hair growth is fueled by hair follicle stem cells (HFSCs). We used ChIP-seq to unfold genome-wide chromatin landscapes of Nfatc1 and dissect the biological relevence of its upstream BMP signaling in HFSC aging. Telogen quies...
ORGANISM(S): Mus musculus 
2013-11-14 | E-GEOD-52328 | biostudies-arrayexpress
MetabolomicsUrine metabolomics phenotyping and urinary biomarker exploratory in mild cognitive impairment and Alzheimer's disease.

INTRODUCTION Alzheimer's disease is a prevalent disease with a heavy global burden and is suggested to be a metabolic disease in the brain in recent years. The metabolome is considered to be the most promising phenotype which reflects changes in genetic, transcript, and protein ...

2024-01-11 | MTBLS8662 | MetaboLights
UnknownSingle-cell and spatial transcriptome analyses reveal tertiary lymphoid structures linked to tumour progression and immunotherapy response in nasopharyngeal carcinoma.
Not available
S-EPMC11375053 | biostudies-literature
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
UnknownTranscriptome analysis of LuxS-deficient Streptococcus mutans grown in biofilms.
Not available
S-EPMC3105442 | biostudies-literature
UnknownProteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues.
Not available
S-EPMC6050252 | biostudies-literature
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