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MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
TranscriptomicsRNA-seq of retinal organoids derived from RPGR patient-, control- and mutation-corrected-iPSC at different developmental stages
Retinitis pigmentosa (RP) is an irreversible and inherited retinopathy. RPGR mutations are the most common causes of this disease. It remains challenging to decipher the mechanism of RPGR mutation because of the lack of appropriate study models. The substitution of patient-specific diseased retina w...
ORGANISM(S): Homo sapiens 
2020-02-01 | E-MTAB-6490 | biostudies-arrayexpress
MetabolomicsGut microbiota-driven regulation of queen bee ovarian metabolism

With the global prevalence of Varroa mites, more and more beekeepers resort to confining the queen bee in a queen cage to control mite infestation or to breed superior and robust queen bees. However, the impact of such practices on the queen bee remains largely unknown. Therefore, we sub...

2023-09-11 | MTBLS7576 | MetaboLights
ProteomicsTMTs-based quantitative proteomic reveals the potential targets of a novel probiotic mixture on seasonal allergic rhinitis
This study examines the effect of a novel multistrain probiotic mixture on symptoms of allergic rhinitis (AR) and investigate potential targets underlying the probiotic treatment using proteomics. All engaged participants in our study are provided with informed consent, and the study design was appr...
ORGANISM(S): Homo Sapiens 
2023-09-28 | PXD045758 |
MetabolomicsMetabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse (NMR assay)
Regulation between the fed and fasted state in mammals is partially controlled by peroxisome proliferator activated receptor-alpha (PPAR-alpha). Expression of the receptor is high in liver, heart and skeletal muscle, but decreases with age. A combined 1H NMR spectroscopy and GC-MS metabolomic approa...
2018-10-11 | MTBLS261 | MetaboLights
UnknownPaleolithic seafaring in East Asia: An experimental test of the dugout canoe hypothesis.
Not available
S-EPMC12189942 | biostudies-literature
ProteomicsMetastatic serum secretome for discovering organ-specific metastasis of lung adenocarcinoma
The metastatic serum samples were collected from LUAD cohort, and were profiled to discover the metastatic serum secretome.
ORGANISM(S): Homo Sapiens 
2024-09-18 | PXD056137 |
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
ProteomicsData indpendent acquisition (DIA) proteomics Analysis of Tobacco Root Tip
Protein expression profiling of root tip of tobacco hybrids and parental was analyzed by data indpendent acquisition proteomics
ORGANISM(S): Nicotiana Tabacum 
2021-09-18 | PXD028624 |
ProteomicsMass spectrometry with DIA quantification of cerebrospinal fluid in 20 subarachnoid hemorrhage patients
We applied mass spectrometry with DIA quantification to identify biomarker candidates in CSF samples from a well-characterized cohort consisted of 20 SAH patients.
ORGANISM(S): Human Csf-associated Densovirus 
2022-03-08 | PXD032118 |
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