Wen Si S - OmicsDI

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Unknown (142)
Metabolomics (7)
Proteomics (6)
Transcriptomics (3)

Organisms

Homo sapiens (5)
Mus musculus (2)
Spirometra erinaceieuropaei (1)

Repository

MetaboLights (7)
biostudies-arrayexpress (3)
iProX (3)
pride (2)
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Tissue

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Disease

Ovarian cancer (1)
Melanoma (1)
Skin melanoma (1)

Technology Type

Mass spectrometry (5)
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All-ion fragmentation (2)
Mass Spectrometry (2)

Instrument Platform

Liquid Chromatography MS - negative - reverse phase (4)
Liquid Chromatography MS - positive - reverse phase (4)
Orbitrap Fusion (1)
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Liquid Chromatography MS - Negative (LC-MS (Negative)) (1)
Liquid Chromatography MS - Positive (LC-MS (Positive)) (1)
Liquid Chromatography MS - negative (1)
Liquid Chromatography MS - positive (1)
Liquid Chromatography MS - positive - HILIC (1)
MS Imaging - (1)
Wates I-Class/XEVO-G2 XS QTOF (1)

Publication Date

2021 (4)
2026 (2)
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2011 (1)
2009 (1)
2007 (1)
2023 (1)
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2022 (1)
2019 (1)
2018 (1)

CHEBI ID

CHEBI:132538 (2)
CHEBI:64525 (2)
CHEBI:66848 (2)
CHEBI:100246 (1)
CHEBI:10056 (1)
CHEBI:10089 (1)
CHEBI:10097 (1)
CHEBI:10130 (1)
CHEBI:1156 (1)
CHEBI:116314 (1)
CHEBI:1235 (1)
CHEBI:1296 (1)
CHEBI:131427 (1)
CHEBI:131428 (1)
CHEBI:131430 (1)
CHEBI:131439 (1)
CHEBI:131440 (1)
CHEBI:131739 (1)
CHEBI:131740 (1)
CHEBI:131993 (1)
CHEBI:132502 (1)
CHEBI:132539 (1)
CHEBI:132542 (1)
CHEBI:132543 (1)
CHEBI:132544 (1)
CHEBI:132582 (1)
CHEBI:132639 (1)
CHEBI:133629 (1)
CHEBI:134192 (1)
CHEBI:134242 (1)

Metabolite Name

(+)-Plicamine (1)
(+)-Prosopinine (1)
(11Z,14Z)-icosadienoic acid (1)
(13Z,16Z)-docosadienoic acid (1)
(15Z)-tetracosenoic acid (1)
(2E,4E)-3,8,8,8-tetrachloro-7-(4-chlorophenyl)-2-hydroxy-6-oxo-octa-2,4-dienoate (1)
(2R,3S)-2-methyl-3-propyloxirane (1)
(2S)-2-hydroxytetradecanoic acid (1)
(3E,5E)-2,6-Dimethyl-1,3,5,7-octatetraene (1)
(5Z,8Z,14Z)-11,12-dihydroxyicosatrienoic acid (1)
(6R)-10-Formyltetrahydropteroyldiglutamate (1)
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid (1)
(E)-2-Butenal (1)
(S)-N-methylcanadine (1)
(S)-p-Mentha-1,8-dien-10-yl acetate (1)
(Z)-13-Hexadecenoic acid (1)
(ent-2alpha,3beta,15beta,16beta)-15,16-Epoxy-2,3-kauranediol (1)
1'H-5alpha-Cholest-2-eno[3,2-b]indole (1)
1,3-Dihydro-(2H)-indol-2-one (1)
1,5-Bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadien-3-one (1)
1-Deoxy-11beta-hydroxypentalenate (1)
1-Deoxypentalenate (1)
1-Hydroxy-2-pentanone (1)
1-Methyl-2-pyrrolecarboxaldehyde (1)
1-Methyladenosine (1)
1-Methylguanine (1)
1-O-oleoyl-sn-glycero-3-phosphocholine (1)
1-Palmitoyl-2-(5-keto-8-oxo-6-octenoyl)-sn-glycero-3-phosphatidylcholine (1)
1-Piperidine carboxylic acid (1)
1-Pyrroline (1)

Study type

Transcription profiling by array (2)
Comparative genomic hybridization by array (1)

Release Date

2022 (24)
2024 (21)
2021 (21)
2025 (18)
2023 (12)
2020 (12)
2019 (8)
2018 (8)
2016 (5)
2017 (3)
2014 (3)
2009 (2)
2015 (2)
2013 (2)
2011 (1)
2007 (1)
2012 (1)
2010 (1)

Lab affiliation

3. College of Pharmacy / International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China, Jinan University, Guangzhou 510632, China (1)
Jinan University (1)

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Gene expression profiles of MCF-7 cells treated with Si-Wu-Tang, estradiol and ferulic acid

Traditional Chinese medicines (TCM), usually composed of a mixture of components, may simultaneously target multiple genes/pathways and thus achieve superior efficacy for complex diseases such as cancer. To identify novel mechanisms of action and potential health benefits for a TCM formula Si-Wu-Tan...

ORGANISM(S): Homo sapiens

2011-05-18 | E-GEOD-23610 | biostudies-arrayexpress

Pharmacological Targeting of Casein Kinase 1δ Suppresses Oncogenic NRAS-Driven Melanoma

Activating mutations in NRAS account for 15-20% of melanoma, yet effective anti-NRAS therapies are still lacking. In this study, we unveil the casein kinase 1δ (CK1δ) as an uncharacterized regulator of oncogenic NRAS mutations, specifically Q61R and Q61K, which are the most prevalent NRAS mutations ...

ORGANISM(S): Homo sapiens (Human)

2024-09-19 | PXD051431 | Pride

Nras melanoma