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UnknownVancomycin associated acute kidney injury in patients with infectious endocarditis: a large retrospective cohort study.
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S-EPMC10679345 | biostudies-literature
ProteomicsIdentification of regulators of polyploidization presents therapeutic targetsfor treatment of AMKL
Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Go...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-01-27 | MSV000078536 | MassIVE
ProteomicsIdentification of a biomarker to predict doxorubicin/cisplatin chemotherapy efficacy for osteosarcoma patients by 4D data-independent acquisition (DIA) mass spectrometry with parallel reaction monitoring (PRM) verification
We analyzed the differentially expressed proteins in 37 resected tissue samples from osteosarcoma patients using paraffin- embedded specimens and 4D data-independent acquisition (DIA) quantitative mass spectrometry to investigate biomarkers for predicting the efficacy of doxorubicin/cisplatin chemot...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD051097 | Pride
Osteosarcoma  doxorubicin/cisplatin chemotherapy efficacy  data-independent acquisition (dia) mass spectrometry with parallel reaction monitoring (prm)  ctsg  neutrophil extracellular traps (nets) 
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
Proteomicscomparative proteomics studies of the wild strain SC1401 and the tfoX deficient strain
Natural transformation, as one of the horizontal gene transfer (HGT) modes of bacteria, allows bacteria to actively uptake foreign DNA under natural conditions and integrate it into their genome through homologous recombination. Natural transformation plays an vital role in the rapid spread of patho...
ORGANISM(S): Glaesserella Parasuis 
2022-03-17 | PXD032382 |
TranscriptomicsSingle-Base Resolution Methylomes of Silkworms and Functional Importance of Gene Methylation in Insects Revealed by Ultra-High-Throughput Sequencing
Single-base resolution DNA methylomes have been accomplished for both Arabidopsis and human cells which have high genome methylation levels by Illumina ultra-high-throughput bisulfite sequencing technology (MethylC-Seq). Here by combining MethylC-Seq and biological replicate strategies we generated ...
ORGANISM(S): Bombyx mori 
2010-04-09 | E-GEOD-18315 | biostudies-arrayexpress
ProteomicsTumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks Nuclear Factor-κB activation in hepatocellular carcinoma
Background: Tumor necrosis factor α-induced protein 1 (TNFAIP1) is frequently downregulated in cancer cell lines and promotes cancer cell apoptosis. However, its role, clinical significance and molecular mechanisms in hepatocellular carcinoma (HCC) are unknown. Methods: The expression of TNFAIP1 in...
ORGANISM(S): Homo Sapiens 
2019-11-19 | PXD016329 |
ProteomicsA brain signaling framework for stress-induced depression and ketamine treatment elucidated by phosphoproteomics
Depression is a common affective disorder characterized by significant and persistent low mood.Ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist, is reported to have a rapid and durable antidepressant effect.
ORGANISM(S): Mus Musculus 
2019-11-18 | PXD016302 |
ProteomicsH3K4me1 directs H3K36me2 and H3K36me3 deposition in land plants
Monomethylation of histone H3 lysine 4 (H3K4me1) marks enhancers in mammals. However, the function of H3K4me1 in plants remains largely unclear. Here, we analyzed the genome-wide distribution of H3K4me1 in diverse species across evolution, revealing a distinctive H3K4me1 distribution pattern in land...
ORGANISM(S): Oryza Sativa 
2025-09-23 | PXD068723 |
ProteomicsArid3b suppresses CD8+ T cell infiltration and function in Microsatellite-stable colorectal cancer via Runx3
Microsatellite stable/proficient mismatch repair (MSS/pMMR) colorectal cancer (CRC) is characterized by a cold tumor microenvironment, marked by sparse CD8⁺ T cell infiltration and resistance to immune checkpoint inhibitors (ICIs). To uncover regulators that limit CD8⁺ T cell infiltration in MSS CRC...
ORGANISM(S): Mus Musculus 
2026-04-16 | PXD077233 |
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