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ProteomicsPIM1 controls GBP1 activity to limit self-damage and guard against pathogen infection
Pathogen virulence factors interfere with various cellular activities, a disruption that can trigger innate immune responses. Interferon-gamma (IFNγ)-inducible antimicrobial factors, such as the guanylate binding proteins (GBPs), promote cell-intrinsic defense against intracellular pathogens by dire...
ORGANISM(S): Toxoplasma gondii PRU Homo sapiens (Human) 
2023-07-26 | PXD029463 | Pride
Pim1 Gbp1 Guanylate binding proteins 14-3-3 Host-pathogen interaction Bystander cells Cell intrinsic immunity 
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