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ProteomicsPIM1 phosphorylation of 14-3-3 ζ in vitro
We previously identified 14-3-3 ζ S64 as a substrate of PIM1 in an in vivo chemical genetic screen. To verify this phosphorylation event and determine whether S64 is the predominant phosphorylation site, we performed in vitro phosphorylation of 14-3-3 ζ by PIM1.
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2021-11-25 | PXD023623 | Pride
Pim1 Protein phosphorylation Kinase 14-3-3 ζ 
TranscriptomicsLoss of Pim1 Imposes a Hyperadhesive Phenotype on Endothelial Cells
Background: PIM1 is a constitutively active serine-threonine kinase regulating cell survival and proliferation. Increased PIM1 expression has been correlated with cancer metastasis by facilitating migration and anti-adhesion. Endothelial cells play a pivotal role in these processes by contributing a...
ORGANISM(S): Mus musculus 
2012-10-29 | E-GEOD-32059 | biostudies-arrayexpress
GenomicsPseudidiomarina marina strain:PIM1
Idiomarina marina PIM1 Genome sequencing and assembly
PRJNA420132 | ENA
TranscriptomicsProviral integration site for Moloney murine leukemia virus (PIM) kinases promote human T helper 1 cell differentiation
The aim of the dataset was to study on genome-wide level the effect of PIM kinase (PIM1+PIM2+PIM3) knockdown in gene expression on early differentiation of human cord blood derived CD4+ T cells cultured under Th1 (Act+IL12) polarizing conditions. Total RNA from PIM1+PIM2+PIM3 siRNA treated cord bloo...
ORGANISM(S): Homo sapiens 
2012-12-05 | E-GEOD-40542 | biostudies-arrayexpress
TranscriptomicsRNAi profiling of human cells with MYC or PIM1 silencing
It has been estimated that about 11% of cellular genes present a functional E box to which MYC can associate on the genome. MYC silencing demonstrated that MYC recruits PIM1 at specific MYC binding sites and confocal microscopy following growth factor treatment, showed an elevated degree of nuclear ...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7960 | biostudies-arrayexpress
GenomicsPim1 exacerbates inflammatory arthritis by mediating Th17 differentiation
Pim1 exacerbates inflammatory arthritis by mediating Th17 differentiation
PRJNA1088323 | ENA
GenomicsBulk RNAseq analysis of wildtype and Pim1-/- macrophages
Bulk RNAseq analysis of wildtype and Pim1-/- macrophages
PRJNA1477407 | ENA
GenomicsRNA-seq analysis of WT and Pim1-/- BMDMs
RNA-seq analysis of WT and Pim1-/- BMDMs
PRJNA801277 | ENA
ProteomicsProteomics of 24 h TCR activated wild-type and Pim1/Pim2 double knockout CD4 and CD8 T cells
T cell antigen-receptor (TCR) and cytokine receptor engagement trigger large changes in Serine/Threonine kinase signalling networks to drive T cell activation and differentiation. The role of only few kinase signalling pathways have been studied in detail, and in this context, Pim kinases are an int...
ORGANISM(S): Mus musculus (Mouse) 
2024-04-15 | PXD051198 | Pride
Lc-msms Mouse Pim1 Pim2 T lymphocyte Pim kinase 
GenomicsRNA sequencing analysis of IECs from WT and PIM1+/- mice
RNA sequencing analysis of IECs from WT and PIM1+/- mice
PRJNA980152 | ENA
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