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ProteomicsIdentification of Antiviral Roles for the Exon-Junction Complex and Nonsense-Mediated Decay in Flaviviral Infection
West Nile virus (WNV) is an emerging mosquito-borne flavivirus, related to dengue virus and Zika virus. To gain insight into host pathways involved in WNV infection, we performed a systematic affinity-tag purification mass spectrometry (AP-MS) study to identify 259 WNV-interacting human proteins. RN...
ORGANISM(S): Homo sapiens (Human) West Nile virus 
2019-11-14 | PXD011728 | Pride
Nonsense-mediated decay Pym1 Virus-host interactions Exon-junction complex Flavivirus West nile virus 
TranscriptomicsExpression data of patient-derived triple negative breast cancer xenograft tumors
Triple negative breast cancer (TNBC) is an aggressive subtype that lack targeted clinical therapies. In addition, TNBC is heterogeneous and was recently further sub-classified into seven TNBC subtypes that displayed unique gene expression patterns. To develop therapeutic treatment regimens, we estab...
ORGANISM(S): Homo sapiens 
2014-03-21 | E-GEOD-47079 | biostudies-arrayexpress
MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine kidney and plasma UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS680 | MetaboLights
UnknownSmaller kidney size at birth in South Asians: findings from the Born in Bradford birth cohort study.
Not available
S-EPMC6071385 | biostudies-literature
UnknownExpression data of patient-derived triple negative breast cancer xenograft tumors
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-47079 | biostudies-other
UnknownRegulation of membrane fluidity by RNF145-triggered degradation of the lipid hydrolase ADIPOR2.
Not available
S-EPMC9531299 | biostudies-literature
UnknownStructural trends in the dehydrogenation selectivity of palladium alloys.
Not available
S-EPMC8159209 | biostudies-literature
UnknownBrazilin cream from Caesalpinia sappan inhibit periodontal disease: in vivo study.
Not available
S-EPMC11229682 | biostudies-literature
UnknownA silent enzootic of an orthopoxvirus in Ghana, West Africa: evidence for multi-species involvement in the absence of widespread human disease.
Not available
S-EPMC2844556 | biostudies-literature
TranscriptomicsRibosome stalling induced by mutation of a CNS-specific tRNA causes neurodegeneration
In higher eukaryotes, the large numbers of nuclear-encoded tRNA genes partially ensure the robustness of cytoplasmic protein translation. Here we discover that a loss-of-function in n-Tr20, a member of the nuclear-encoded tRNA Arg UCU family that is expressed specifically in the central nervous syst...
ORGANISM(S): Mus musculus 
2014-07-28 | E-GEOD-56127 | biostudies-arrayexpress
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