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FGF21 is a liver-derived hormone. FGF21 expression and secretion from hepatocytes is potently induced in response to fasting. However, the significance of such fasting-induced hepatokine production is poorly understood. Here, we investigated the putative effect of hepatocyte-derived FGF21 on fasting...
ORGANISM(S): Mus musculus 
FGF21 is a liver-derived hormone. It is potently induced and secreted in response to fasting. However, the biological significance of this endocrine response remains poorly understood. Here, we investigated the effect of hepatocyte FGF21 on perigonadic white adipose tissue biology through the analys...
ORGANISM(S): Mus musculus 
The counts of total white blood cells (WBCs) and WBC subsets are well-established diagnostic factors for various diseases. It has been shown that variations in WBC counts are significantly controlled by individuals’ genetics in swine. However, despite detection of quantitative trait loci (QTLs) for ...
ORGANISM(S): Sus scrofa 
In order to decipher the molecular alterations caused by the growing medium, we harvested the roots of plants grown in hydroponics and on soil for 6 weeks under 10-hour short days. The temperature was 20°C (day and night), the relative humidity was 70 %, and the light was provided by cool-white fl...
ORGANISM(S): Arabidopsis thaliana 
Homeorhetic mechanisms assist dairy cows to transition from pregnancy to lactation. In some cows this is less successful and they develop severe negative energy balance, placing them at risk of metabolic and infectious disease and reduced fertility. We placed Holstein Friesian cows into metabolicall...
ORGANISM(S): Bos taurus 
Understanding the human milk metabolome can help inform infant nutrition and health. Untargeted metabolomics was used to study breast milk from 31 healthy participants to assess the shared metabolites in milk from participants with various backgrounds and understand how different demographic, health...
2024-10-04 | MTBLS2419 | MetaboLights
High throughput transcriptomics using the TempO-Seq (TM) platform for dose response modelling of 3 different cell lines treated with multiple compounds as part of a study to generate a toolbox and workflow for non-animal safety assessments. The data generated here was produced as one part of a toolb...
ORGANISM(S): Homo sapiens 
Immune traits (ITs) are potentially relevant criteria to characterize individualM-bM-^@M-^Ys immunocompetence. Thus, porcine ITs related to innate and adaptive immunity were studied by functional genomics approaches, with no initial focus on resistance to specific pathogens. Peripheral blood transcr...
ORGANISM(S): Sus scrofa 
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