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TranscriptomicsPho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevated Temperature or Hsp90 Compromise [ChIP-chip]
The capacity to sense and transduce temperature signals pervades all aspects of biology, and temperature exerts powerful control over the development and virulence of diverse pathogens. In the leading fungal pathogen of humans, Candida albicans, temperature has a profound impact on morphogenesis, a ...
ORGANISM(S): Candida albicans 
2012-03-20 | E-GEOD-34938 | biostudies-arrayexpress
TranscriptomicsPho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by Elevated Temperature or Hsp90 Compromise [mRNA]
The capacity to sense and transduce temperature signals pervades all aspects of biology, and temperature exerts powerful control over the development and virulence of diverse pathogens. In the leading fungal pathogen of humans, Candida albicans, temperature has a profound impact on morphogenesis, a ...
ORGANISM(S): Candida albicans 
2012-03-20 | E-GEOD-34255 | biostudies-arrayexpress
TranscriptomicsExpression of C. albicans genes during GI tract colonization and influence of efg1, efh1 and cph1 mutations
The goals of this study were to identify the Efg1p-regulon during GI tract colonization and to compare C. albicans gene expression during colonization of different organs of the GI tract. Our results identified significant differences in gene expression between cells colonizing the cecum and ileum. ...
ORGANISM(S): Candida albicans 
2013-02-08 | E-GEOD-41771 | biostudies-arrayexpress
TranscriptomicsA toolbox for epitope-tagging and genome-wide location analysis in Candida albicans
Background : Candida albicans is a diploid pathogenic fungus not yet amenable to routine genetic investigations. Understanding aspects of the regulation of its biological functions and the assembly of its protein complexes would lead to further insight into the biology of this common disease-causing...
ORGANISM(S): Candida albicans 
2010-05-16 | E-GEOD-13427 | biostudies-arrayexpress
TranscriptomicsTranscription Factor Substitution during the Evolution of Fungal Ribosome Regulation_ChIP-CHIP
Coordinated ribosomal protein (RP) gene expression is crucial for cellular viability, but the transcriptional network controlling this regulon has only been well characterized in the yeast Saccharomyces cerevisiae. We have used whole-genome transcriptional and location profiling to establish that, i...
ORGANISM(S): Candida albicans 
2010-05-25 | E-GEOD-10458 | biostudies-arrayexpress
TranscriptomicsTranscription Factor Substitution during the Evolution of Fungal Ribosome Regulation_expression profiling
Coordinated ribosomal protein (RP) gene expression is crucial for cellular viability, but the transcriptional network controlling this regulon has only been well characterized in the yeast Saccharomyces cerevisiae. We have used whole-genome transcriptional and location profiling to establish that, i...
ORGANISM(S): Candida albicans 
2010-05-25 | E-GEOD-10499 | biostudies-arrayexpress
TranscriptomicsTranscriptional Response of Candida albicans Cells Following Phagocytosis by Mouse Macrophages
Transcriptional profiling of Candida albicans that had been phagocytosed for 1, 2, or 4 hours by either bone marrow-derived mouse macrophaged (BMDM) or immortalized RAW264.7 cells Keywords: Time course Two-condition experiment, phagocytosed cells vs cells maintained in D-10 media. Time course: 1, 2,...
ORGANISM(S): Candida albicans 
2008-07-28 | E-GEOD-11399 | biostudies-arrayexpress
TranscriptomicsExperimental annotation of the human pathogen Candida albicans coding and noncoding transcribed regions using high resolution tiling arrays
Compared to other model organisms and despite the clinical relevance of the pathogenic yeast Candida albicans, no comprehensive analysis has been done to provide experimental support of its in silico-based genome annotation. Here we have undertaken a genome-wide experimental annotation to accurately...
ORGANISM(S): Candida albicans 
2010-07-07 | E-GEOD-22625 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of Ppr1 gain of function mutant Candida albicans strains
Metabolic pathways are largely conserved in eukaryotes, but the transcriptional regulation of these pathways can sometimes vary between species; this has been termed rewiring. Recently it has been established that in the Saccharomyces lineage starting from Saccharomyces castelli, genes involved in a...
ORGANISM(S): Candida albicans 
2016-04-06 | E-GEOD-79931 | biostudies-arrayexpress
TranscriptomicsSte18p is a positive control element in the mating process of Candida albicans
Disruption of STE18 gene which encodes a γ subunit of a heterotrimeric G protein in Candida albicans is shown to block pheromone-induced gene expression. Ectopic expression of either the Gα or the Gβ subunit of the heterotrimeric G protein is able to restore pheromone-induced gene expression. The...
ORGANISM(S): Candida albicans 
2014-01-14 | E-GEOD-54031 | biostudies-arrayexpress
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