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MetabolomicsCharacterization of Whole Blood EVs Using PRotein Organic Solvent PRecipitation

Blood plays a vital role in diagnostic medicine by providing essential information for assessing health and diagnosing various conditions. Routine blood tests can reveal important biomarkers that support early diagnosis and timely intervention. Recently, extracellular vesicles (EVs) have emerged ...

2026-08-24 | MTBLS12801 | MetaboLights
MetabolomicsPROMIS, global analysis of PROtein-Metabolite Interactions using Size separation in Arabidopsis thaliana
Small molecules not only represent cellular building blocks and metabolic intermediates, but also regulatory ligands and signaling molecules that interact with proteins. Although these interactions affect cellular metabolism, growth, and development, they have been largely understudied. Herein, we d...
2018-07-19 | MTBLS94 | MetaboLights
MetabolomicsA targeted MRM-based lipidomic dataset of Tenebrio molitor larvae fed diets with different protein levels
Tenebrio molitor is increasingly used as a sustainable source of nutrients for food and feed production, yet their lipid metabolic responses to dietary protein remain poorly characterized at the molecular species level. Here, we report a targeted UPLC–MS/MS lipidomics dataset of Tenebrio molitor lar...
2026-05-20 | MTBLS14531 | MetaboLights
MetabolomicsThe Immediate Metabolomic Effects of Whole Genome Duplication in the Greater Duckweed Spirodela polyrhiza

We use untargeted metabolomics to investigate the immediate phytochemical effects of autopolyploidy on our model system, the greater duckweed Spirodela polyrhiza, a small aquatic macrophyte from the family Lemnaceae. We compare metabolite abundances in four genetically distinct diploid-a...

2024-09-16 | MTBLS10435 | MetaboLights
ProteomicsWhole body and venom proteomes of Eunicella Singularis
This datasets contain the proteomes relative to the whole body protein extract and to the chemically discharged nematocysts of the white gorgonian Eunicella singularis (Octocorallia) to investigate its venom composition.
ORGANISM(S): Eunicella singularis 
2025-02-28 | PXD061313 | Pride
Nematocyst Eunicella singularis Venom Octocorallia Soft coral 
MetabolomicsFatty acid transport protein 4 is required for incorporation of saturated ultralong-chain fatty acids into epidermal ceramides and monoacylglycerols
Fatty acid transport protein 4 (FATP4) is an acyl-CoA synthetase that is required for normal permeability barrier in mammalian skin. FATP4 (SLC27A4) mutations cause ichthyosis prematurity syndrome, a nonlethal disorder. In contrast, Fatp4-/- mice die neonatally from a defective barrier. H...
2021-07-15 | MTBLS1138 | MetaboLights
MetabolomicsMetabolomics analysis was used to resolve metabolites affecting the protein oil content of soybean.
Soybean (Glycine max (L.)) originated in China more than 5000 years ago, and the country is currently the third largest producer of soybeans in the world (Hymowitz et al., 2015). Based on a wild soybean Chromosome Segment Substitution Line (CSSL) population were constructed by crossing with the cult...
2024-11-13 | MTBLS9424 | MetaboLights
TranscriptomicsTranscriptional profiling of Caenorhabditis elegans whole-organism extract and subsequent co-immune precipitation of mRNA with the poly-A binding protein FLAG::PAB-1 specifically expressed in body wall muscle cells.
Tissue specific microarray data is obtained by generating a whole-organism extract and subsequent co-immune precipitation of mRNA with the poly-A binding protein FLAG::PAB-1 specifically expressed in body wall muscle cells (Roy et al. 2002). Different lines were compared: SV911 (control), SV912 (CY...
ORGANISM(S): Caenorhabditis elegans 
2011-11-25 | E-TABM-886 | biostudies-arrayexpress
MetabolomicsUPLC-QE-Orbitrap-MS-Based Metabolomics and Gut Microbiome Analysis to Reveal Codonopsis pilosula (Franch.) Nannf. Extract Improves Cyclophosphamide-Induced Immunosuppression in Mice

Immune system dysfunction leads to recurrent or severe infections, increased susceptibility to concurrent illnesses, and heightened risk of tumors. Current immunomodulators often carry side effects, whereas phytotherapy offers relative stability, making this therapeutic approach worthy of explora...

2026-02-03 | MTBLS13825 | MetaboLights
TranscriptomicsClariomS Array to determine the impact of whole body adenylyl cyclase 5 (Adcy5) knockout on male/female epigonadal white adipos tissue (eWAT) gene expression
We analyzed the effect of whole body Adcy5 knockout on adipose tissue gene expression profiles. Therefore, we isolated RNA, examined RNA integrity and concentration on an Agilent Fragment Analyzer using the HS RNA Kit. cRNA was prepared from 100 ng of total RNA hybridized to GeneChip Clariom S array...
ORGANISM(S): Mus musculus 
2021-04-19 | E-MTAB-9417 | biostudies-arrayexpress
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