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ProteomicsWhole saliva baseline proteome profile - head and neck cancer
Oral mucositis (OM) is a common, painful and often treatment-limiting side effect of radiotherapy (RT) for head and neck cancer (HNC) patients. Unstimulated saliva was collected before the first radiotherapy application in 50 HNC patients. 41 out of 50 patients developed OM (grade III) during radiot...
ORGANISM(S): Homo sapiens (Human) 
2016-07-04 | PXD003230 | Pride
Lc-ms/-ms Whole saliva 
ProteomicsProteomic Analysis of Whole Saliva in Chronic Periodontitis
Periodontitis is a chronic inflammatory disease resulting from a dysbiosis of the dental biofilm and a dysregulated host response in susceptible individuals. It is characterized by periodontal attachment destruction, bone resorption, and eventual tooth loss. Salivary biomarkers have been sought to p...
ORGANISM(S): Homo sapiens (Human) 
2020-05-20 | PXD015024 | Pride
Saliva  periodontitis  periodontal health  proteome  mass spectrometry 
ProteomicsLabel-free quantitative proteomics versus antibody-based assays to measure neutrophil derived enzymes in saliva
Discovery-based quantitative proteomics identified dozens of novel protein candidates in saliva, yet none are clinically qualified. Mass spectrometry (MS) has been recognized as newer 'gold standard' for the identification and analysis of individual proteins in complex biological samples due to high...
ORGANISM(S): Homo sapiens (Human) 
2019-12-20 | PXD015220 | Pride
Saliva Huamn experimental gingivitis 
ProteomicsComparisons of Whole Saliva and Cell Free Saliva by DIA-Based Proteome Profiling
Saliva has emerged as a promising diagnostic resource due to its accessibility, non-invasiveness, and repeatability, enabling early disease detection and timely intervention. However, current studies often overlook the distinction between whole saliva (WS) and cell-free saliva (CFS). This study aims...
ORGANISM(S): Homo Sapiens 
PXD055371 |
ProteomicsEvaluation of suitability of dried saliva spots for in-depth proteome analyses of clinical applications
We performed a single-shot DIA-MS proteome analysis of dried saliva spots (DSS) to investigate whether it provides a platform to complement the dried blood spot (DBS) data.
ORGANISM(S): Homo Sapiens (human) 
2022-04-26 | PXD031181 | JPOST Repository
ProteomicsEvaluation of suitability of dried saliva spots for in-depth proteome analyses of clinical applications - Additional file
We performed a single-shot DIA-MS proteome analysis of dried saliva spots (DSS) to investigate whether it provides a platform to complement the dried blood spot (DBS) data.
ORGANISM(S): Homo Sapiens (human) 
2022-04-26 | PXD032116 | JPOST Repository
ProteomicsProteomics of saliva, plasma, and salivary gland tissue in Sjögren’s syndrome and non-Sjögren patients identify novel biomarker candidates
Objective: The aim of this study was to characterize and compare the proteome in whole saliva, plasma, and salivary gland tissue in patients with primary Sjögren’s syndrome (pSS) and patients having symptoms of pSS, but not fulfilling the classification criteria, and to search for diagnostic biomark...
ORGANISM(S): Homo sapiens (Human) 
2020-07-09 | PXD016231 | Pride
Saliva Plasma Sjögren’s syndrome Proteomics Biomarker Minor salivary glands 
ProteomicsAnalysis of low molecular weight protein profile in whole saliva with special reference to ovulation
Whole saliva is contains major, minor and gingival crevicular fluid/secretions and it plays vital role in maintaining the oral health, three pair of major salivary glands consist of parotid, submandibular and sub-lingual glands. Saliva is a good biological fluid to explore health and disease stat...
ORGANISM(S): Homo sapiens (Human) 
2016-12-22 | PXD000921 | Pride
Saliva Lc-msms Ovulation Protein Cystatin 
ProteomicsTick host range adaptation: changes in protein profiles in Ixodes scapularis and Amblyomma americanum saliva during stimulation to feed on different hosts
Understanding the molecular basis of how the tick adapts to feed on different animal hosts is central to understanding tick and tick-borne disease (TBD) epidemiology. Tick adaptation to feed on vertebrate hosts is regulated by tick secretion of multiple tick saliva proteins (TSPs) and other molecule...
ORGANISM(S): Ixodes scapularis (Black-legged tick) (Deer tick) Amblyomma americanum 
2022-02-28 | PXD007712 | Pride
Tick-host relationship Saliva Tick Proteomic Host adaptation 
UnknownAnalysis of age and gender associated N-glycoproteome in human whole saliva.
Not available
S-EPMC4070402 | biostudies-literature
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