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TranscriptomicsTranscription profiling of C. elegans used as an assay system for endocrine disruptors
In order to assist in the identification of possible endocrine disrupting chemicals (EDC) in groundwater, we are developing Caenorhabolitis elegans as a high throughput bioassay system in which responses to EDC may be detected by gene expression using DNA microarray analysis. As a first step we exam...
ORGANISM(S): Caenorhabditis elegans 
2005-06-29 | E-SMDB-2701 | biostudies-arrayexpress
UnknownSensitive quantification of m.3243A>G mutational proportion in non-retinal tissues and its relationship with visual symptoms.
Not available
S-EPMC8895728 | biostudies-literature
ProteomicsProteomic Profiling of Mammalian COPII Vesicles
By combining in vitro COPII vesicle reconstitutions and SILAC-based mass spectrometric analysis this study aims to identify the core proteome of mammalian COPII vesicles. Furthermore proteomes generated from vesicles with different Sec24 isoforms have been investigated with the same approach to iden...
ORGANISM(S): Homo sapiens (Human) 
2019-01-07 | PXD012128 | Pride
Silac Copii vesicels Proteomics 
UnknownThe Muscarinic Acetylcholine M2 Receptor-Induced Nitration of p190A by eNOS Increases RhoA Activity in Cardiac Myocytes.
Not available
S-EPMC10605742 | biostudies-literature
UnknownRGS3L allows for an M2 muscarinic receptor-mediated RhoA-dependent inotropy in cardiomyocytes.
Not available
S-EPMC8888479 | biostudies-literature
UnknownM2 muscarinic receptors induce airway smooth muscle activation via a dual, Gbetagamma-mediated inhibition of large conductance Ca2+-activated K+ channel activity.
Not available
S-EPMC3258941 | biostudies-literature
UnknownAn Advanced 'clickECM' That Can be Modified by the Inverse-Electron-Demand Diels-Alder Reaction.
Not available
S-EPMC9291553 | biostudies-literature
Proteomicsc-di-GMP-induced conformational dynamics of the c-di-GMP-binding protein A (CdbA) from Myxococcus xanthus
The second messenger c-di-GMP has important functions in response to changing environmental and cellular cues in bacteria. Here, we report the identification of CdbA, a DNA binding protein of the ribbon-helix-helix family in Myxococcus xanthus, and show that it binds c-di-GMP in vitro. CdbA is essen...
ORGANISM(S): Myxococcus xanthus DK 1622 
2020-04-16 | PXD018028 | Pride
C-di-gmp Plgs Hdx-ms Dynamx 
TranscriptomicsTranscriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal.
The expansion of the neocortex during mammalian brain evolution results primarily from an increase in neural progenitor cell divisions in its two principal germinal zones during development, the ventricular zone (VZ) and the subventricular zone (SVZ). Using mRNA sequencing, we analyzed the transcrip...
ORGANISM(S): Homo sapiens 
2012-07-02 | E-GEOD-38805 | biostudies-arrayexpress
UnknownTotal synthesis and target identification of marine cyclopiane diterpenes.
Not available
S-EPMC11686375 | biostudies-literature
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