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MetabolomicsLongitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
ProteomicsMspire-Simulator: LC-MS shotgun proteomic simulator for creating realistic gold standard data - HEK cell lysate
The most important step in any quantitative proteomic pipeline is feature detection (aka peak picking). However, generating quality hand-annotated data sets to validate the algorithms, especially for lower abundance peaks, is nearly impossible. An alternative for creating gold standard data is to si...
ORGANISM(S): Homo sapiens (Human) 
2020-01-24 | PXD000477 | Pride
Human Ms-simulator Hek-293t Fasp 
TranscriptomicsExpression data from human triploid and diploid fibroblast cell cultures
Dosage compensation restores a balanced network of gene expression between autosomes and sex chromosomes in males (XY) and females (XX). In mammals, this is achieved by doubling the expression of X-linked genes in both sexes, together with X inactivation in females. X up-regulation may be controlled...
ORGANISM(S): Homo sapiens 
2009-11-06 | E-GEOD-18877 | biostudies-arrayexpress
TranscriptomicsCharacterization and comparison of lactating mouse and bovine mammary gland miRNomes
Background: The mammary gland is a dynamic organ that undergoes important physiological changes during reproductive cycles. Until now, data regarding the characterisation of miRNA in the mammary gland have been scarce and mainly focused on their abnormal expression in breast cancer. Our goal was to ...
ORGANISM(S): Bos taurus 
2014-03-24 | E-GEOD-53511 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of epidydimal fat pads in mice following high fat and normal diets to study insulin resistance and obesity
Gene transcription profiling in Epidydimal fat pad (EPD) following High fat versus normal diet in C57/Bl6 mice. Characterisation of molecular mechanisms of in vivo insulin action in mouse models of experimentally induced Insulin resistance. Switched the...
ORGANISM(S): Mus musculus 
2013-01-30 | E-BAIR-12 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver following high fat and normal diets to study insulin resistance and obesity
Gene transcription profiling in liver following high fat versus normal diet in C57/Bl6 mice. Characterisation of molecular mechanisms of in vivo insulin action in mouse models of experimentally induced Insulin Resistance. ...
ORGANISM(S): Mus musculus 
2013-01-30 | E-BAIR-10 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of epidydimal fat pads in mice at different time points following high fat and normal diets to study insulin resistance and obesity
Gene transcription profiling in Epidydimal fat pad (EPD) following High fat versus normal diet in C57/Bl6 mice. The diet was switched when mice were 5 weeks old, then samples taken at 2 days, 8 days, 3 weeks and 15 weeks.
ORGANISM(S): Mus musculus 
2013-01-30 | E-BAIR-9 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of muscle cells in mice at different different time points following muscle and normal diets to study insulin resistance and obesty
Gene transcription profiling in muscle following muscle versus normal diet in C57/Bl6 mice. Switched the diet when mice were 5 weeks old, then sampled at 8 days, 3 weeks and 15 weeks.
ORGANISM(S): Mus musculus 
2013-01-30 | E-BAIR-11 | biostudies-arrayexpress
GenomicsGenomeEUtwin Data Access Committee
Access to data generated by the GenomeEUtwin is available by emailing application to the data access committee and will be granted to qualified investigators for appropriate use.
EGAC00000000007 | EGA
TranscriptomicsCIT_VADS_BW_OMICS
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net); Integrative study based on 89 patients with Head and Neck Squamous Cell Carcinoma (HNSCC); 89 Affymetrix HG-U133 Plus 2.0 GeneChips arrays; 88 samples on HumanCNV370-Quad Ge...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-MTAB-1328 | biostudies-arrayexpress
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