Sort   by:  
 Page size 
TranscriptomicsTempo-Seq experiment relating to Next Generation Risk Assessment for Occupational Chemical Safety – a Real World Example with Sodium-2-hydroxyethane sulfonate
A dose response and human cell line comparison of transcriptional responses following treatment with the chemical compound Sodium-2-hydroxyethane sulfonate. Gene expression changes were used to estimate the POD - minimum effect concentration when a biological perturbation as estimated by gene exp...
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-14069 | biostudies-arrayexpress
TranscriptomicsEHMT1 and EHMT2 inhibition induce fetal hemoglobin expression [RNA-seq]
Using UNC0638 and genetic assays to inhibit EHMT1/2 and derepress fetal hemoglobin in adult hematopoietic cells. RNA-Seq in primary adult human erythroid cells treated with UNC0638 or the vehicle control (DMSO) in biological triplicates.
ORGANISM(S): Homo sapiens 
2015-11-02 | E-GEOD-71421 | biostudies-arrayexpress
TranscriptomicsAn Advancement in Developmental and Reproductive Toxicity (DART) Risk Assessment: Evaluation of a Bioactivity and Exposure-Based NAM Toolbox
High throughput transcriptomics using the TempO-Seq (TM) platform for dose response modelling of 3 different cell lines treated with multiple compounds as part of a study to generate a toolbox and workflow for non-animal safety assessments. The data generated here was produced as one part of a toolb...
ORGANISM(S): Homo sapiens 
2025-09-15 | E-MTAB-15274 | biostudies-arrayexpress
TranscriptomicsAdvancing systemic toxicity risk assessment: Evaluation of a NAM-based toolbox approach
High throughput transcriptomics using the TempO-Seq (TM) platform for dose response modelling of 3 different cell lines treated with multiple compounds as part of a study to generate a toolbox and workflow for non-animal safety assessments. The data generated here was produced as one part of a toolb...
ORGANISM(S): Homo sapiens 
2025-09-15 | E-MTAB-15266 | biostudies-arrayexpress
TranscriptomicsAre Non-animal Systemic Safety Assessments Protective: A Toolbox and Workflow
High throughput transcriptomics using the TempO-Seq (TM) platform for dose response modelling of 3 different cell lines treated with multiple compounds as part of a study to generate a toolbox and workflow for non-animal safety assessments. The data generated here was produced as one part of a toolb...
ORGANISM(S): Homo sapiens 
2025-09-15 | E-MTAB-15258 | biostudies-arrayexpress
TranscriptomicsCoordinated regulation of cell cycle transcripts by p53-inducible microRNAs, miR -192 and -215
Cell cycle arrest in response to DNA damage is an important anti-tumorigenic mechanism. microRNAs (miRNAs) were shown recently to play key regulatory roles in cell cycle progression. For example, miR-34a is induced in response to p53 activation and mediates G1 arrest by down-regulating multiple ce...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-13105 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lymphocytes from 1240 Mexican Americans for the discovery of expression QTLs
Transcriptional profiles were generated for lymphocyte samples from 1,240 randomly ascertained, mostly non-diseased Mexican American participants in the San Antonio Family Heart Study. Research findings related to the genetic regulation of expression levels are published in the following article: Go...
ORGANISM(S): Homo sapiens 
2008-01-01 | E-TABM-305 | biostudies-arrayexpress
UnknownInferring structural variant cancer cell fraction.
Not available
S-EPMC7002525 | biostudies-literature
UnknownEnhancing cognitive performance prediction by white matter hyperintensity connectivity assessment.
Not available
S-EPMC11629703 | biostudies-literature
TranscriptomicsThe Populus transciptome in elevated CO2 reveals increased anthocyanin biosynthesis during delayed autumnal senescence
Over recent decades the progression of natural autumnal senescence has been increasingly delayed across wide areas of the Northern Hemisphere and is thought to be caused by rising temperature. Recently this delay has been shown to be partly attributable to rising atmospheric carbon dioxide concentr...
ORGANISM(S): Populus x canadensis 
2010-01-31 | E-GEOD-15874 | biostudies-arrayexpress
Sort   by:  
 Page size