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MetabolomicsSerum metabolomic profiles associated with postmenopausal hormone use

INTRODUCTION: Postmenopausal hormone use is linked to several health outcomes and the risk associated with some may differ depending on whether estrogen is used alone or in combination with progestin.

OBJECTIVE: Metabolomic analyses of postmenopausal hormon...

2019-06-02 | MTBLS136 | MetaboLights
TranscriptomicsGene profiling of keloid fibroblasts shows altered expression in multiple fibrosis-associated pathways
Keloids are benign tumors of the dermis that form during a protracted wound healing process. Susceptibility to keloid formation occurs predominantly in people of African and Asian descent. The key alteration(s) responsible for keloid formation has not been identified and there is no satisfactory t...
ORGANISM(S): Homo sapiens 
2007-11-26 | E-GEOD-7890 | biostudies-arrayexpress
TranscriptomicsMouse CD4+/CD8+ thymocytes from miR-181a1/b1 KO vs WT
miR-181a1/b1, miR-181a2/b2, and miR-181c/d belong to a highly conserved family of microRNA clusters, yet their role in vivo is poorly understood. Here we show that the miR-181a1/b1 cluster is absolutely essential for NKT development and is a critical determinant of thymocyte proliferation, survival ...
ORGANISM(S): Mus musculus 
2014-04-09 | E-GEOD-41090 | biostudies-arrayexpress
TranscriptomicsGenome-wide localization of Ino80 and Arp5 on chromosome in Saccharomyces cerevisiae
Background: Chromatin remodeling complexes facilitate the access of enzymes that mediate transcription, replication or repair of DNA by modulating nucleosome position and/or composition. Ino80 is the DNA-dependent Snf2-like ATPase subunit of a complex whose nucleosome remodeling activity requires ac...
ORGANISM(S): Saccharomyces cerevisiae 
2008-04-10 | E-GEOD-9233 | biostudies-arrayexpress
TranscriptomicsGenome-wide localization of Ino80 on chromosome in Saccharomyces cerevisiae
Background: Chromatin remodeling complexes facilitate the access of enzymes that mediate transcription, replication or repair of DNA by modulating nucleosome position and/or composition. Ino80 is the DNA-dependent Snf2-like ATPase subunit of a complex whose nucleosome remodeling activity requires ac...
ORGANISM(S): Saccharomyces cerevisiae 
2008-04-10 | E-GEOD-9420 | biostudies-arrayexpress
TranscriptomicsThe effect of Sparstolonin B (SsnB) on gene expression in HCAECs
Sparstolonin B is a novel bioactive compound isolated from Sparganium stoloniferum, an herb historically used in Traditional Chinese Medicine as an anti-tumor agent. SsnB has previously demonstrated anti-angiogenic properties. In functional assays, SsnB inhibited endothelial cell tube formation (M...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-GEOD-44596 | biostudies-arrayexpress
TranscriptomicsIno80 chromatin remodeling complex promotes recovery of stalled replication forks
This SuperSeries is composed of the following subset Series: GSE9233: Genome-wide localization of Ino80 and Arp5 on chromosome in Saccharomyces cerevisiae GSE9420: Genome-wide localization of Ino80 on chromosome in Saccharomyces cerevisiae Keywords: SuperSeries Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae 
2008-04-10 | E-GEOD-9421 | biostudies-arrayexpress
UnknownThe Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.
Not available
S-EPMC5984804 | biostudies-literature
TranscriptomicsAn Atlas of Bovine Gene Expression Reveals Novel Distinctive Tissue Characteristics and Evidence for Improving Genome Annotation
Background: A comprehensive transcriptome survey, or "gene atlas", provides information essential for a complete understanding of the genomic biology of an organism. We present an atlas of RNA abundance for 92 adult, juvenile and fetal cattle tissues and 3 cattle cell lines. Results: The ...
ORGANISM(S): Bos taurus 
2010-09-28 | E-GEOD-21544 | biostudies-arrayexpress
UnknownGlobal surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries.
Not available
S-EPMC5879496 | biostudies-literature
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