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UnknownSelf-Administration of Auricular Acupuncture in Rural Veterans with Chronic Pain: A Pilot Project.
Not available
S-EPMC8729899 | biostudies-literature
ProteomicsLocus-specific proteomics identifies CHD4 and Polycomb PRC1 as novel repressors of Epstein-Barr virus lytic reactivation
The Epstein Barr virus (EBV) is a human gammaherpesvirus which infects over 90% of the global population and is associated with lymphoid and epithelioid cancers. After infection, EBV enters a latent state in B-cells where the viral genome persists as a nuclear episome maintained by expression of a s...
ORGANISM(S): Homo sapiens (Human) 
2026-02-11 | PXD068122 | Pride
Epigenetics Virus activation Locus specific proteomics Polycomb complex Epstein-barr virus Virus latency Nurd complex De-ubiquitinase 
ProteomicsFunctional proteomic atlas of HIV-infection in primary human CD4+ T cells
Viruses manipulate host cells to enhance their replication, and the identification of host factors targeted by viruses has led to key insights in both viral pathogenesis and cellular physiology. We previously described global changes in cellular protein levels during human immunodeficiency virus (HI...
ORGANISM(S): Homo sapiens (Human) 
2019-03-08 | PXD012263 | Pride
Proteomics Hiv Primary t-cells 
ProteomicsAntagonism of PP2A is an independent and conserved function of HIV-1 Vif and causes cell cycle arrest
The seminal description of cellular restriction factor APOBEC3G and its antagonism by HIV-1 Vif has underpinned two decades of research on the host-virus interaction. As well as APOBEC3G and its homologues, however, we have recently discovered that Vif is also able to degrade the PPP2R5 family of re...
ORGANISM(S): Homo sapiens (Human) 
2020-04-17 | PXD018271 | Pride
Hiv Pp2a Proteomics Vif 
ProteomicsAnti-sense oligonucleotide inhibited iSAT reaction
Investigating the intricate and rapid folding kinetics of large RNA-protein complexes (RNPs), like the bacterial ribosome, remains a formidable challenge in structural biology. Previous genetic approaches to probe assembly have focused on modulating the expression of either r-proteins or assembly fa...
ORGANISM(S): Escherichia coli 
2025-07-28 | PXD064127 | Pride
Sucrose gradient fractions Isat Ribosome biogenesis 
ProteomicsQuantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-Cov-2 innate immune evasion
We used two model systems to characterise the changes caused by SARS-CoV-2 using quantitative proteomics. We used primary human epithelial cells differentiated at the air-liquid interface, first describing the relative abundance of proteins found in each major cell type of the epithelium, and then c...
ORGANISM(S): Homo sapiens (Human) 
2022-05-26 | PXD034135 | Pride
Sars-cov-2 Hbec 
UnknownReporting the whole story: Analysis of the 'out-of-scope' questions from the James Lind Alliance Teenage and Young Adult Cancer Priority Setting Partnership Survey.
Not available
S-EPMC8483195 | biostudies-literature
ProteomicsRegulation of membrane fluidity by RNF145-triggered degradation of the lipid hydrolase ADIPOR2
The regulation of membrane lipid composition is critical for cellular homeostasis. Cells are particularly sensitive to phospholipid saturation, with increased saturation causing membrane rigidification and lipotoxicity. How mammalian cells sense membrane lipid composition and reverse fatty acid (FA)...
ORGANISM(S): Homo sapiens (Human) 
2022-08-10 | PXD034835 | Pride
Ap-ms Tmt Oritrap fusion 
ProteomicsGlobal coordination of metabolic pathways in Escherichia coli by active and passive regulation
In this study, we identify the regulatory mechanisms that coordinate catabolism and anabolism in the bacterium Escherichia coli. Integrating protein, metabolite, and metabolic flux changes in genetically implemented gradual catabolic or anabolic limitations, we show that a combination of global and ...
ORGANISM(S): Escherichia Coli K-12 (ncbitaxon:83333) 
2021-03-03 | MSV000086992 | MassIVE
ProteomicsComparative proteomic analysis of black tiger prawn (Penaeus monodon) and white leg prawn (Litopenaeus vannamei) allergen profiles
Shellfish allergy is a major global health concern, with prawns being among the most common elicitors of allergic reactions. This project describes a comparative allergenomic analysis of the most widely consumed prawn species worldwide: black tiger prawn (Penaeus monodon) and white leg prawn (Litop...
ORGANISM(S): Penaeus 
2026-09-07 | PXD072307 | Pride
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