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TranscriptomicsTargets of the transcription factor Brachyury in differentiating mouse ES cells
Brachyury (or T) is expressed in the primitive streak, tailbud and notochord of the early mouse embryo (Herrmann et al., 1990; Wilkinson et al., 1990). It plays a key role in early development: mouse embryos lacking functional Brachyury protein fail to gastrulate properly, do not form a differentiat...
ORGANISM(S): Mus musculus 
2012-05-28 | E-GEOD-16646 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis of Human Diabetic Kidney Disease (Control Glomeruli vs. Control Tubuli)
We identified 1,700 differentially expressed probesets in DKD glomeruli and 1,831 in diabetic tubuli; 330 probesets were commonly differentially expressed in both compartments. The canonical complement signaling pathway was determined to be statistically differentially regulated in both DKD glomerul...
ORGANISM(S): Homo sapiens 
2011-08-02 | E-GEOD-30566 | biostudies-arrayexpress
UnknownCorrelation of the treatment sensitivity of patient-derived organoids with treatment outcomes in patients with head and neck cancer (SOTO): protocol for a prospective observational study.
Not available
S-EPMC11474813 | biostudies-literature
TranscriptomicsTranscriptome Analysis of Human Diabetic Kidney Disease (DKD Glomeruli vs. Control Glomeruli)
We identified 1,700 differentially expressed probesets in DKD glomeruli and 1,831 in diabetic tubuli; 330 probesets were commonly differentially expressed in both compartments. The canonical complement signaling pathway was determined to be statistically differentially regulated in both DKD glomerul...
ORGANISM(S): Homo sapiens 
2011-08-02 | E-GEOD-30528 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis of Human Diabetic Kidney Disease (DKD Tubuli vs. Control Tubuli)
We identified 1,700 differentially expressed probesets in DKD glomeruli and 1,831 in diabetic tubuli; 330 probesets were commonly differentially expressed in both compartments. The canonical complement signaling pathway was determined to be statistically differentially regulated in both DKD glomerul...
ORGANISM(S): Homo sapiens 
2011-08-02 | E-GEOD-30529 | biostudies-arrayexpress
UnknownThe subcellular distribution of miRNA isoforms, tRNA-derived fragments, and rRNA-derived fragments depends on nucleotide sequence and cell type.
Not available
S-EPMC11397057 | biostudies-literature
ProteomicsCab45-dependent facilitation of insulin secretory granule biogenesis and its dysregulation in type 2 diabetes
Germanos M1*. Yau B1*. Taper M1. An Y1. Yeoman C1. Wilson A1. Cattin-Ortolá J2. Maslar D3. Tong J1. Naghiloo S1. Needham E4. Diaz-Vegas A4. Larance M1. Thomas H5. Seidah NG6. von Blume J7. James DE4. Thorn P1. Ailion M2. Asensio C3. Kebede MA1. 1 School of Medical Sciences, Charles Perkins Centre, ...
ORGANISM(S): Rattus rattus (Black rat) 
2024-12-02 | PXD052042 | Pride
Islet Cab45 Insulin 
UnknownLymphocyte subset expression and serum concentrations of PD-1/PD-L1 in sepsis - pilot study.
Not available
S-EPMC5902875 | biostudies-literature
MetabolomicsHypusination Orchestrates the Antimicrobial Response of Macrophages
Innate responses of myeloid cells defend against pathogenic bacteria via inducible effectors. Deoxyhypusine synthase (DHPS) catalyzes the transfer of the N-moiety of spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form the amino acid hypusine. Hypusinate...
2021-04-06 | MTBLS607 | MetaboLights
UnknownElevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells.
Not available
S-EPMC12398951 | biostudies-literature
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