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TranscriptomicsTranscription profiling of S. cerevisiae during prolonged maltose limited cultivation
Prolonged cultivation (>25 generations) of Saccharomyces cerevisiae in aerobic, maltose-limited chemostat cultures led to profound physiological changes. Maltose hypersensitivity was observed when cells from prolonged cultivations were suddenly exposed to excess maltose. This substrate hypersensitiv...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-8897 | biostudies-arrayexpress
ProteomicsB-cell-specific MYD88 L252P expression causes a premalignant gammopathy resembling IgM MGUS
A highly recurrent, somatic L265P mutation in the TIR domain of the signaling adapter MYD88 constitutively activates NF-kB. It occurs in nearly all human patients with Waldenström’s macroglobulinemia (WM), a B cell malignancy caused by IgM-expressing cells. Here we introduced an inducible leucine to...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-06 | PXD017292 | Pride
Lymphoid neoplasia 
GenomicIL-17 Signaling in Midbrain Neurons in Parkinson's Disease

To determine IL-17-induced global transcriptome changes in midbrain neurons derived from induced pluripotent stem cells (iPSC) from three sporadic Parkinson's disease (PD) patients and three age- and sex-machted controls, deep RNA sequencing (RNA-Seq) of IL-17-treated and untreated PD and con...

phs001686 | dbGaP
TranscriptomicsEngineering topology and kinetics of sucrose metabolism in Saccharomyces cerevisiae for improved ethanol yield
Sucrose is a major carbon source for industrial bioethanol production by Saccharomyces cerevisiae. In yeasts, two modes of sucrose metabolism occur: (i) extracellular hydrolysis by invertase, followed by uptake and metabolism of glucose and fructose, and (ii) uptake via sucrose-H+ symport followed b...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-05 | E-GEOD-30535 | biostudies-arrayexpress
ProteomicscpFHy - An FMN hydrolase of the haloacid dehalogenase superfamily is active in plant chloroplasts
RL2
ORGANISM(S): Pisum sativum (Garden pea) 
2011-11-07 | PRD000237 | Pride
TranscriptomicsNovel biomarkers for distributed stem cells: asymmetric self-renewal associated (ASRA) genes identification by combined cDNA micro-array orthogonal intersection and sparse feature analysis
Biomarkers unique for distributed stem cells (DSCs) have proven elusive. Previous searches for proteins expressed specifically in DSCs were hampered by difficulty obtaining pure DSCs and challenges to successfully mining complex molecular expression data. To identify novel candidates for DSC bioma...
ORGANISM(S): Mus musculus 
2014-06-30 | E-GEOD-40183 | biostudies-arrayexpress
UnknownInvestigation on the true identity of Entomobryanigriventris Stach, 1929 (Collembola, Entomobryidae) with the description of a new species.
Not available
S-EPMC10716847 | biostudies-literature
UnknownStability/activity tradeoffs in Thermusthermophilus HB27 laccase.
Not available
S-EPMC7085441 | biostudies-literature
TranscriptomicsConditional Essentiality of vicK (walKSpn) Histidine Kinase for Anaerobic Growth of Streptococcus pneumoniae D39
The VicRK two-component system of S. pneumoniae (Pneumococcus) is a member of the essential WalRK (YycFG) family found in low G+C gram positive bacteria. Previously, we showed that phosphorylated VicR response regulator (RR) is essential, because of its strong positive regulation of the pcsB gene, w...
ORGANISM(S): Streptococcus pneumoniae 
2013-01-04 | E-GEOD-19752 | biostudies-arrayexpress
ProteomicsInteraction of iron oxide nanoparticles with human plasma
The Interaction of iron oxide nanoparticles with human plasma was studied.
ORGANISM(S): Homo sapiens (Human) 
2019-04-11 | PXD004441 | Pride
Protein corona Inflammation Iron oxide nanoparticles Complement 
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