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TranscriptomicsTranscriptome analysis in nutrient deficient wheat roots
Microarrays were used to identify transcriptional responses in field-grown root material of wheat in order to dissect specific gene expression responses to limited macronutrient availability, particularly phosphate. This study fills the gap between the transcriptome studies on model plants and the l...
ORGANISM(S): Triticum aestivum 
2015-04-01 | E-GEOD-61679 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wheat meiosis and microsporogenesis in hexaploid bread wheat
Our understanding of the mechanisms that govern the cellular process of meiosis is limited in higher plants with polyploid genomes. Bread wheat is an allohexaploid that behaves as a diploid during meiosis. Chromosome pairing is restricted to homologous chromosomes despite the presence of homoeologue...
ORGANISM(S): Triticum aestivum 
2008-06-14 | E-GEOD-6027 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analyses of anti-adipogenic effects of oleuropein in human mesenchymal stem-cells
The main goal of the present work was to use an in vitro adipogenic-differentiation mode, with mesenchymal stem-cells (MSC) from human bone-marrow, to study whole-transcriptomic differential gene-expression when such cells are induced to differentiate into adipocytes in absence or presence of oleuro...
ORGANISM(S): Homo sapiens 
2018-12-31 | E-MTAB-5211 | biostudies-arrayexpress
UnknownIdentification of genomic regions associated with cereal cyst nematode (Heterodera avenae Woll.) resistance in spring and winter wheat.
Not available
S-EPMC10090075 | biostudies-literature
ProteomicsThe Human Disease Gene LYSET is Essential for Lysosomal Enzyme Transport and Viral Infection
Lysosomes are key degradative compartments of the cell. Transport to lysosomes ismediated by tagging soluble enzymes with mannose 6-phosphate (M6P) by GlcNAc-1-phosphotransferase whose deficiency leads to the severe lysosomal storage disorder mucolipidosisII (MLII). Several viruses require lysosomal...
ORGANISM(S): Mus musculus (Mouse) 
2022-09-15 | PXD029609 | Pride
Data independent acquisition (dia) Tmem 251 Parallel reaction monitoring (prm) Targeted ms Label free quantification Mouse embryonic fibroblasts 
ProteomicsTargeted Quantification of the Lysosomal Proteome in Complex Samples
The lysosome, as the main degradative organelle of eukaryotic cells, is involved in numerous cellular processes. A defect in one of its proteins often results in lysosomal storage diseases (LSDs). For the study of lysosomal proteins, mass spectrometry (MS) has emerged as the method of choice. Lysoso...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-08 | PXD023278 | Pride
Targeted proteomics Parallel reaction monitoring Label-free quantification Lysosomes Data-independent acquisition 
TranscriptomicsRNA-seq data on leaf 8 blade tissue of 62 individual Brassica napus (Darmor) plants grown in the field.
62 individual Brassica napus plants of the same accession grown in the same field were expression-profiled in autumn 2016 and phenotyped extensively until harvest in spring 2017. Machine learning models were used to link gene expression to the phenotypes of individual plants, with the purpose of ass...
ORGANISM(S): Brassica napus 
2022-10-10 | E-MTAB-11904 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wheat GF-transgenic-B102,1-1 vs control-L88-31 lines endosperm tissue (14 and 28 days post anthesis-dpa) and in leaf tissue (8 days post germination ?dpg)
The high molecular weight (HMW) subunits of wheat glutenin are synthesised only in the starchy endosperm tissue of the developing wheat grain. We studied the effect of introducing transgenes on the global gene expression profiles of selected transgenic wheat lines, particularly during wheat seed dev...
ORGANISM(S): Triticum aestivum 
2005-10-05 | E-MEXP-306 | biostudies-arrayexpress
ProteomicsProteomic interactome analyses of Glypican 1 and a putative disease modifying variant
In an 8-year-old girl of consanguineous Turkish parents, who developed ataxic gait and polyneuropathy at the age of 3 years, we identified a biallelic missense variant c.424C>T, p.R142W in Glypican 1 (GPC1) by using whole genome sequencing. Up to date, GPC1 has not been associated with a neuromuscul...
ORGANISM(S): Homo sapiens (Human) 
2023-08-15 | PXD040023 | Pride
Gpc1 Dia-ms Ip Human 
UnknownElectrostatic dust collectors compared to inhalable samplers for measuring endotoxin concentrations in farm homes.
Not available
S-EPMC4850132 | biostudies-literature
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