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human dermal fibroblasts were treated with 100 ng/ml recombinant mouse Wnt 3a for 8 h and 24 h and compared to untreated controls at 8 and 24 h. RNA was isolated and microarray analysis was performed with Illumina Human Sentrix-6 BeadChip arrays
ORGANISM(S): Homo sapiens 
To investigate successful maintenance of skin epithelial stem cells (EpSCs) in vitro using Wnt-3a, we prepared CD49f+CD34+ cells, an EpSC-rich population from adult mouse skin and cultured for 10 days in the presence of Wnt-3a. Sorted CD49f+CD34+ cells proliferated markedly in the presence of Wnt-3a...
ORGANISM(S): Mus musculus 
Wnt Phospho protein profiling comparing control and Fto deficient cell after Wnt3a stimulation Control vs Fto deficient MEFs treated with Wnt 3a condioned medium for 40 minutes. 6 replicates per array
ORGANISM(S): Mus musculus 
Frizzleds (FZD) function as receptors for secreted lipoglycoproteins of the Wingless/Int-1 (WNT) family, initiating an important signal transduction network in multicellular organisms. FZDs are classified as G protein-coupled receptors (GPCRs), which control a wide variety of physiological functions...
ORGANISM(S): Homo sapiens (Human) 
2018-10-18 | PXD011173 | Pride
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