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GenomicsTargeted alveolar regeneration with Frizzled-specific agonists
Targeted alveolar regeneration with Frizzled-specific agonists
PRJNA860972 | ENA
TranscriptomicsFrizzled 4 regulates stemness and invasiveness of migrating glioma cells established by serial in vivo intracranial transplantation
One of the most detrimental hallmarks of glioblastoma multiforme (GBM) is cellular invasiveness, considered a potential cause of tumor recurrence. Infiltrated GBM cells are difficult to completely eradicate surgically and with local therapeutic modalities. Although much effort has focused on unders...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-21570 | biostudies-arrayexpress
ProteomicsFrizzled receptors facilitate Tiki inhibition of Wnt signaling at the cell surface
Tiki antagonizes Wnt3a signaling by cleaving and inactivating Wnt3a in Wnt-producing cells. Tiki also functions in Wnt-receiving cells to antagonize Wnt signaling by an unknown mechanism. Here, we demonstrate that Tiki inhibition of Wnt signaling at the cell surface requires Frizzled receptors. Tiki...
ORGANISM(S): Homo sapiens (Human) 
2023-05-24 | PXD040942 | Pride
Tiki Lrp6 Ror1/2 Wnt Fzd 
UnknownRegulation of endothelial cell cytoskeletal reorganization by a secreted frizzled-related protein-1 and frizzled 4- and frizzled 7-dependent pathway: role in neovessel formation.
Not available
S-EPMC2189632 | biostudies-literature
UnknownInhibition of Wnt/β-catenin signaling by a soluble collagen-derived frizzled domain interacting with Wnt3a and the receptors frizzled 1 and 8.
Not available
S-EPMC3267734 | biostudies-literature
GenomicsSecreted-frizzled-related protein 5 modulates calcium handling in human iPSC-cardiomyocytes
Secreted-frizzled-related protein 5 modulates calcium handling in human iPSC-cardiomyocytes
PRJNA1001988 | ENA
UnknownNon-Coding RNA and Frizzled Receptors in Cancer.
Not available
S-EPMC8521042 | biostudies-literature
TranscriptomicsFZD7 Plays a Critical Role in Triple Negative Breast Cancer Proliferation
Breast cancer is genetically and clinically heterogeneous. Triple negative cancer (TNBC) is a subtype of breast cancer usually associated with poor outcome and lack of benefit from target therapy. A pathway analysis in a microarray study was performed using TNBC compared with non-triple negative bre...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-27447 | biostudies-arrayexpress
TranscriptomicsFz1Fz2 double knock out mouse palate microarray (E13.5)
The closure of an open anatomical structure by the directed growth and fusion of two tissue masses is a recurrent theme in mammalian embryology, and this process plays an integral role in the development of the palate, ventricular septum, neural tube, urethra, diaphragm, and eye. In mice, targeted ...
ORGANISM(S): Mus musculus 
2010-09-22 | E-GEOD-24276 | biostudies-arrayexpress
UnknownFrizzled Receptors in Development and Disease.
Not available
S-EPMC5103317 | biostudies-literature
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