Ror1/2 - OmicsDI

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CHEBI ID

CHEBI:180628 (1)
CHEBI:180627 (1)
CHEBI:89514 (1)
CHEBI:180626 (1)
CHEBI:180625 (1)
CHEBI:180624 (1)
CHEBI:86090 (1)
CHEBI:34575 (1)
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CHEBI:90693 (1)
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CHEBI:31108 (1)
CHEBI:163908 (1)
CHEBI:180619 (1)
CHEBI:57784 (1)
CHEBI:180618 (1)
CHEBI:158093 (1)
CHEBI:75018 (1)
CHEBI:28392 (1)
CHEBI:180617 (1)
CHEBI:164847 (1)
CHEBI:180616 (1)
CHEBI:180615 (1)
CHEBI:180614 (1)
CHEBI:180613 (1)
CHEBI:5320 (1)
CHEBI:180612 (1)
CHEBI:180611 (1)

Metabolite Name

P-Vinylbiphenyl (1)
Oxalic acid-guanidine (1/1) (1)
1,6-di-o-phosphonohex-2-ulofuranose (1)
Dibutyl terephthalate (1)
(R)-4-Amino-5-(tert-butoxy)-5-oxopentanoic acid (1)
L-Glutarylcarnitine (1)
4,4'-Methylenediphenol (1)
Dehydrofelodipine (1)
U-0126 (1)
Methyl 3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-thiohexopyranoside (1)
N'-[2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]-4-nitrobenzohydrazide (1)
1-(3-Isocyanatophenyl)-5-(methylsulfanyl)-1H-tetrazole (1)
Gly-Met-Val (1)
3-Aminopentanoic acid (1)
2-[3-Carboxy-3-(methylammonio)propyl]-L-histidine (1)
Ala-Ala-Gly-Ala (1)
Ala-Gln-Ala (1)
4-Dedimethylamine-4-oxo-anhydro-7-Cl-tetracycline (1)
Trp-Ser-Pro (1)
Gly-Gly-Thr-Tyr (1)
4-Hydroxy-5-phenyl-1,3-oxazinan-2-one (1)
3,4-Methylenedioxybenzyl methyl ketoximine (1)
Methyl 4,4,4-trifluoro-3-hydroxy-3-methoxybutanoate (1)
Thr-Tyr-Gly-Gly (1)
Gentioflavine (1)
Asp-Thr-His-Gly (1)
Acetic acid-1-(2-ethoxyethoxy)ethan-1-ol (1/1) (1)
Terestigmine (1)
Glu-Cys-Gly (1)
2-Deoxy-2,3-didehydro-N-glycoloylneuraminic acid (1)

First Public Date

2014 (2)
2025 (1)
2023 (1)
2017 (1)

Study type

Transcription profiling by array (31)
ChIP-seq (11)
RNA-seq of coding RNA (9)
Methylation profiling by array (2)
RNA-seq of coding RNA from single cells (2)
ChIP-chip by tiling array (1)
Animal - Single-cell sequencing (1)
RNA-seq of non coding RNA (1)

Release Date

2015 (14)
2014 (9)
2022 (9)
2016 (8)
2013 (8)
2010 (8)
2023 (7)
2021 (6)
2020 (5)
2018 (5)
2017 (5)
2024 (5)
2011 (4)
2025 (4)
2008 (3)
2019 (3)
2012 (2)
2007 (1)

Lab affiliation

Moffitt Cancer Center Tampa, FL, USA (1)
The Key Laboratory for Human Disease Gene Study of Sichuan Province and the Department of Laboratory Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China (1)

Tags

xref:PubMed:41790934 (1)
xref:PubMed:28695110 (1)
xref:PubMed:37096681 (1)

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Wnt5a induces ROR1 to recruit DOCK2 to activate Rac1/2 in chronic lymphocytic leukemia.

Not available

S-EPMC6043980 | biostudies-literature

Wnt5a enhances proliferation of chronic lymphocytic leukemia and ERK1/2 phosphorylation via a ROR1/DOCK2-dependent mechanism.

Not available

S-EPMC8062590 | biostudies-literature

Frizzled receptors facilitate Tiki inhibition of Wnt signaling at the cell surface

Tiki antagonizes Wnt3a signaling by cleaving and inactivating Wnt3a in Wnt-producing cells. Tiki also functions in Wnt-receiving cells to antagonize Wnt signaling by an unknown mechanism. Here, we demonstrate that Tiki inhibition of Wnt signaling at the cell surface requires Frizzled receptors. Tiki...

ORGANISM(S): Homo sapiens (Human)

2023-05-24 | PXD040942 | Pride

The UC San Diego Chronic Lymphocytic Leukemia (CLL) Study

The UC San Diego Chronic Lymphocytic Leukemia Study is designed to identify genetic, epigenetic, and transcriptional changes important for CLL. This data release consists of samples collected to 1) identify genomic changes associated with CLL progression using serially collected tumor samples; 2)...

phs000767 | dbGaP

Pan-Tissue and -Cancer Analysis of ROR1 and ROR2 Transcript Variants Identify Novel Functional Significance for an Alternative Splice Variant of ROR1.

Not available

S-EPMC9599429 | biostudies-literature

Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation.

Not available

S-EPMC4731190 | biostudies-literature

ROR1 is upregulated in endometrial cancer and represents a novel therapeutic target.

Not available

S-EPMC7431863 | biostudies-literature

Wnt5a induces ROR1 to associate with 14-3-3ζ for enhanced chemotaxis and proliferation of chronic lymphocytic leukemia cells.

Not available