Wnt signaling is critical for the development and maintenance of many cell lineages, including hematopoietic stem cells (HSCs). Tight regulation of Wnt signals is essential, as overactivation can drive tumorigenesis. Numerous Wnt ligands and Frizzled (Fzd) receptors exist, and the negative regulatio...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) Helicobacter pylori J99 (Campylobacter pylori J99)