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TranscriptomicsRNAi knock down of VCP in human HeLa cells
Study of the effects of the VCP knockdown. VCP (p97, yeast cdc48) is a hexameric AAA ATPase involved in various cellular functions including degradation of proteins by the ubiquitin-proteasome system. We examine the consequences of the reduction of VCP levels after RNAi of VCP in HeLa cells. We find...
ORGANISM(S): Homo sapiens 
2006-08-23 | E-MEXP-817 | biostudies-arrayexpress
ProteomicsIdentification of proteins associated with the human mitochondrial degradosome
The human mitochondrial degradosome is a complex of the ribonuclease PNPase (Q8TCS8, encoded by PNPT1 gene) and RNA helicase SUV3 (Q8IYB8, encoded by SUPV3L1 gene). The aim of the project was to identify proteins which co-purify with both subunits of the degradosome. To this end we used human 293 ce...
ORGANISM(S): Homo sapiens (Human) 
2018-07-06 | PXD009826 | Pride
Mitochondrial rna Supv3l1 Suv3 Pnpt1 Mitochondrial degradosome Pnpase 
TranscriptomicsThe influence of WWOX tumor supressor gene on endometrial cancerogenesis
The WWOX gene is a tumor suppressor probably involved in variety of cellular processes including and is ferquently downregulated in variety of cancer types. However, its role in endometrial cancerogenesis is not well described. The aim of this study was to characterize how WWOX may be involved in ...
ORGANISM(S): Homo sapiens 
2014-09-03 | E-GEOD-61041 | biostudies-arrayexpress
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