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UnknownMitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology.
Not available
S-EPMC12616538 | biostudies-literature
UnknownProceedings of the 10th annual deep brain stimulation think tank: Advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, interventional psychiatry, and women in neuromodulation.
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S-EPMC9933515 | biostudies-literature
MetabolomicsComparative Metabolomic Sampling of Upper and Lower Airways by Four Different Methods to Identify Biochemicals That May Support Bacterial Growth
Bacteria need nutrients from the host environment to survive, yet we know little about which biochemicals are present in the airways (the metabolome), which of these biochemicals are essential for bacterial growth and how they change with airway disease. The aims of this pilot study were to develop ...
2019-06-13 | MTBLS179 | MetaboLights
TranscriptomicsGene Expression in Castration-Resistant C4-2 Cells after AR Knockdown
Prostate cancer is the most common, lethal malignancy in men. Although androgen withdrawal therapies are used to treat advanced disease, progression to a castration-resistant, end-stage is the usual outcome. In this study, the tested hypothesis was that the androgen receptor remains essential for th...
ORGANISM(S): Homo sapiens 
2010-06-23 | E-GEOD-13332 | biostudies-arrayexpress
ProteomicsGlycoprofile Comparison of SARS-CoV-2 Spike Proteins Expressed in CHO and HEK Cell Lines
This study assessed the N-glycosylation profiles of a full-length trimeric spike protein expressed in either HEK or CHO cells. Glycopeptide analysis was performed using a tandem mass spectrometry workflow and BioPharma Finder™ using HEK and CHO glycan databases for protein characterisation. The resu...
ORGANISM(S): Homo sapiens (Human) 
2025-09-15 | PXD054718 | Pride
Covid-19 Hek cells Ms-ms Sars-cov-2 N-glycosylation Cho cells 
UnknownDAP12 deletion reduces neuronal SLIT2 and demyelination and enhances brain resilience in female tauopathy mice.
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S-EPMC12673724 | biostudies-literature
UnknownIntegrating Geriatric Assessment Measures into National Cancer Institute Clinical Trials.
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S-EPMC9949568 | biostudies-literature
UnknownAnti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injury.
Not available
S-EPMC11197196 | biostudies-literature
ProteomicsProteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma
Resistance to proteasome inhibitors (PIs) is a ubiquitous clinical concern in multiple myeloma. We proposed that signaling-level responses after PI would reveal new means to enhance efficacy. Unbiased phosphoproteomics after the PI carfilzomib surprisingly demonstrated the most prominent phosphory...
ORGANISM(S): Homo sapiens (Human) 
2020-02-21 | PXD012172 | Pride
Cancer Multiple myeloma Splice factor Spliceosome Lc-msms phosphoproteomics Proteasome inhibition Splicing Alternative splicing 
UnknownTau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Not available
S-EPMC10166855 | biostudies-literature
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