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ProteomicsXanthohumol Activity-Based Probes Targeting Flavonoid Catabolism
Xanthohumol, the principle prenylflavonoid found in hops (Humulus lupulus), is a potential anti-inflammatory agent in the gut. To investigate the interactions between xanthohumol and catabolic gut bacteria, and its role in the anti-inflammatory pathway, a suite of xanthohumol-derived activity-based ...
ORGANISM(S): Eubacterium Ramulus (ncbitaxon:39490) Escherichia Coli (ncbitaxon:562) 
2022-02-04 | MSV000088789 | MassIVE
ProteomicsInduction of active hepatic cytochrome P450 enzymes in mice exposed to benzo[a]pyrene or environmental mixtures of polycyclic aromatic hydrocarbons
Cytochrome P450 enzymes play an important role in bioactivating or detoxifying polycyclic aromatic hydrocarbons (PAHs). We exposed mice to doses of benzo[a]pyrene (BaP) or a mixture of PAHs to characterize dose- and time-response relationships of specific cytochrome P450s. Mice exposed to the highes...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-13 | PXD019472 | Pride
Enyzme induction Chemoproteomics Polycyclic aromatic hydrocarbons Cytochrome p450 
ProteomicsChemical profiling of live cell temporal redox dynamics in a photoautotrophic cyanobacterium
We have developed a quantitative chemical probe approach for live cell labeling of proteins that are sensitive to redox modifications. We utilize this in vivo strategy coupled to mass spectrometry-based proteomics to identify 176 proteins undergoing ~5-10 fold dynamic redox change in response to nut...
ORGANISM(S): Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum) 
2015-08-24 | PXD000329 | Pride
Cyanobacteria Photosynthesis Chemical profiling Redox Biofuels 
ProteomicsFetal to adult ontogeny of human cytochrome P450 activity, abundance, and expression
Activity-based and global proteomic analysis of fetal through late adulthood human samples, with a primary focus on cytochrome P450 enzyme expression and functional activity
ORGANISM(S): Homo sapiens (Human) 
2018-10-24 | PXD002781 | Pride
Activity-based proteomics Ontogeny Cytochrome p450 
ProteomicsA Survey of Serine Hydrolase Activity in Mycobacterium tuberculosis
Changes in Serine Hydrolase Activity Associated with Mycobacterium tuberculosis Replication
ORGANISM(S): Mycobacterium tuberculosis 
2016-02-01 | PXD002763 | Pride
Replication Serine hydrolase 
ProteomicsDinitrogenase functionality in Cyanothece 51142 during nutrient limitation
Dinitrogenase functions as an electron valve to prevent ROS in Cyanothece 51142 during nutrient limitation
ORGANISM(S): Cyanothece sp. (strain ATCC 51142) 
2018-10-24 | PXD002841 | Pride
Dinitrogenase Nutrient Electron valve 
TranscriptomicsInteractome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus
Relatively little is understood about the dynamics of global host–pathogen transcriptome changes that occur during bacterial infection of mucosal surfaces. To test the hypothesis that group A Streptococcus (GAS) infection of the oropharynx provokes a host transcriptome response, we performed genom...
ORGANISM(S): Macaca fascicularis 
2010-03-18 | E-GEOD-20262 | biostudies-arrayexpress
UnknownA multi-site randomized trial of a clinical decision support intervention to improve problem list completeness.
Not available
S-EPMC10114117 | biostudies-literature
UnknownEarly Intratracheal Budesonide to Reduce Bronchopulmonary Dysplasia in Extremely Preterm Infants: The Budesonide in Babies (BiB) Randomized Clinical Trial.
Not available
S-EPMC12486137 | biostudies-literature
UnknownGenetic modifiers of liver disease in cystic fibrosis.
Not available
S-EPMC3711243 | biostudies-literature
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