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TranscriptomicsmiRNA 135b regulation of inflammation
RT-PCR analysis of inflammatory cytokines and receptors in pEGP-miR-135b over-expressing cells compard to controls (pEGP-miR-null) using pathway-specific PCR arrays for the evaluation of mouse inflammatory cytokines and receptors (#PAMM-011D). qPCR array gene expression profiling. This experiment ex...
ORGANISM(S): Mus musculus 
2013-01-31 | E-GEOD-43681 | biostudies-arrayexpress
TranscriptomicsmiRNA 135b regulation by Il1r1 during inflammation
RT-PCR analysis of inflammatory cytokines and receptors following Il1alpha treatment of pEGP-miR-135b over-expressing cells compard to controls (pEGP-miR-null) using pathway-specific PCR arrays for the evaluation of mouse inflammatory cytokines and receptors (#PAMM-011D). qPCR array gene expression ...
ORGANISM(S): Mus musculus 
2013-01-31 | E-GEOD-43683 | biostudies-arrayexpress
TranscriptomicsPulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage
Polycyclic aromatic hydrocarbons (PAHs) are widely distributed, carcinogenic environmental contaminants produced as a consequence of the incomplete combustion of fossil fuels. Benzo[a]pyrene (BaP) is a very extensively studied prototypical PAH. We recently reported a complete lack of change in micro...
ORGANISM(S): Mus musculus 
2011-10-03 | E-GEOD-24751 | biostudies-arrayexpress
TranscriptomicsChanges in cholesterol homeostasis and acute phase response following pulmonary exposure to multi-walled carbon nanotubes links carbon nanotube exposure to risk of cardiovascular disease
Adverse lung effects in rodents following pulmonary exposure to multi-walled carbon nanotubes (MWCNT) are well documented. However, systemic effects are less understood. Prospective epidemiological studies have shown increased cardiovascular disease risk after pulmonary exposure to airborne particle...
ORGANISM(S): Mus musculus 
2015-02-02 | E-GEOD-61366 | biostudies-arrayexpress
ProteomicsMonitoring rapid degradation of NANOG reveals UTP15 maintains pluripotency by regulating nascent transcripts
Master transcription factor (mTF) has been recognized as topmost regulatory hierarchy in cell fate determination. However, the direct transcriptional targets of mTFs, and how the interplay between these transcriptional targets and their associated RNA-binding proteins (RBPs) orchestrate the realisat...
ORGANISM(S): Mus musculus (Mouse) 
2025-10-28 | PXD043911 | Pride
Mouse Mesc 
ProteomicsThe new landscape of differentially expression proteins in placenta tissues of gestational diabetes based on iTRAQ proteomics
Proteomics screening of the DEPs of the normal and GDM maternal placentas was conducted by using isobaric tags for relative and absolute quantitation (iTRAQ). The bioinformatics analysis was performed on DEPs, and parallel reaction monitoring (PRM) was used to verify the DEPs. Sixty-eight DEPs in G...
ORGANISM(S): Homo Sapiens 
PXD033280 |
ProteomicsProteomics of Camellia oleifera seeds at different development stages
iTRAQ-based comparative proteomic analysis of C. oleifera would greatly improve the understanding of its seed ripening process.
ORGANISM(S): Camellia Oleifera 
PXD021909 |
TranscriptomicsIntratracheally Instilled Titanium Dioxide Nanoparticles Translocate to Heart and liver and Activate Complement Cascade in the Heart of C57BL/6 Mice (Liver)
An estimated 1% or less of the nanoparticles (NPs) deposited in lungs translocate to systemic circulation and enter other organs; however this estimation may not be accurate considering the low sensitivity of the existing in vivo NP detection methods. Moreover, the biological outcomes of such low le...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-56325 | biostudies-arrayexpress
TranscriptomicsIntratracheally Instilled Titanium Dioxide Nanoparticles Translocate to Heart and liver and Activate Complement Cascade in the Heart of C57BL/6 Mice (Heart)
An estimated 1% or less of the nanoparticles (NPs) deposited in lungs translocate to systemic circulation and enter other organs; however this estimation may not be accurate considering the low sensitivity of the existing in vivo NP detection methods. Moreover, the biological outcomes of such low le...
ORGANISM(S): Mus musculus 
2015-03-31 | E-GEOD-56324 | biostudies-arrayexpress
TranscriptomicsPulmonary miRNA expression in C57BL/6 Bom Tac mice (dams) intratracheally instilled with Printex 90 carbon black nanoparticles
miRNAs were measured in pregant mice exposed to vehicle control (nanopure water) or a cumulative dose of 0.268 mg Printex 90 in vehicle by intratracheal instillation and sacrificed at weaning (26-27 days after exposure). Pregnant mice were exposed to vehicle control (nanopure water) or a cumulative ...
ORGANISM(S): Mus musculus 
2012-04-01 | E-GEOD-36170 | biostudies-arrayexpress
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