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UnknownPolycystin-2 expression is regulated by a PC2-binding domain in the intracellular portion of fibrocystin.
Not available
S-EPMC2581563 | biostudies-literature
UnknownSabotaging of the oxidative stress response by an oncogenic noncoding RNA.
Not available
S-EPMC5240659 | biostudies-literature
UnknownMolecular dynamics of β-hairpin models of epigenetic recognition motifs.
Not available
S-EPMC3482467 | biostudies-literature
UnknownMapping mania symptoms based on focal brain damage.
Not available
S-EPMC7524493 | biostudies-literature
MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
MetabolomicsLipopolysaccharides from Ralstonia solanacearum induce a broad metabolomic response in Solanum lycopersicum

Ralstonia solanacearum, one of the most destructive crop pathogens worldwide, causes bacterial wilt disease in a wide range of host plants. The major component of the outer membrane of Gram-negative bacteria, lipopolysaccharides (LPS), has been shown to function as elicitors of plant defense lead...

2023-08-08 | MTBLS7324 | MetaboLights
UnknownDisruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects.
Not available
S-EPMC124907 | biostudies-literature
ProteomicsActinomycin targets NPM1c-primed mitochondria in AML
Acute myeloid leukemia (AML) pathogenesis often involves a mutation in the NPM1 nucleolar chaperone, but the bases for its transforming properties and association with favorable outcome remain incompletely understood. Here we demonstrate that an oncogenic mutant form of NPM1 (NPM1c) hampers formatio...
ORGANISM(S): Homo sapiens (Human) 
2021-12-17 | PXD025507 | Pride
Pml Lfq Actinomycin d Mitochondria Npm1c Qexactive Senescence 
TranscriptomicsAnalysis of gene expression in human Bronchial Alveolar Lavage Cell (BAL) cell pellets
Clinical subphenotypes of asthma are characterized by pathological, cellular, and molecular heterogeneity of the airway. Gene expression profiling of airway inflammatory cells in diseased patients by microarray analysis will provide insight into the molecular heterogeneity and support the developmen...
ORGANISM(S): Homo sapiens 
2016-01-06 | E-GEOD-74986 | biostudies-arrayexpress
UnknownNo contribution of IP3-R(2) to disease phenotype in models of dilated cardiomyopathy or pressure overload hypertrophy.
Not available
S-EPMC4028972 | biostudies-literature
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