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UnknownClinical role of microRNAs in cytogenetically normal acute myeloid leukemia: miR-155 upregulation independently identifies high-risk patients.
Not available
S-EPMC3731981 | biostudies-literature
UnknownPrognostic significance of the European LeukemiaNet standardized system for reporting cytogenetic and molecular alterations in adults with acute myeloid leukemia.
Not available
S-EPMC3518729 | biostudies-literature
UnknownAge-related prognostic impact of different types of DNMT3A mutations in adults with primary cytogenetically normal acute myeloid leukemia.
Not available
S-EPMC3295550 | biostudies-literature
UnknownEpigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score.
Not available
S-EPMC3918538 | biostudies-literature
TranscriptomicsA gp130-induced Src/Yes-YAP Cascade Links Inflammation to Regeneration in the Mammalian Intestine
gp130Act cDNA was PCR-amplified and inserted into a plasmid containing the 12.4-kb Villin promoter. The 15.7-kb expression cassette was excised by PmeI digestion, purified, and injected into fertilized C57BL/6 oocytes to obtain founder mice, two of which transmitted the gp130Act transgene. Small int...
ORGANISM(S): Mus musculus 
2015-02-21 | E-MTAB-2400 | biostudies-arrayexpress
ProteomicsTumour mtDNA mutations drive aerobic glycolysis to enhance checkpoint blockade (part 2)
Mitochondrial DNA (mtDNA) encodes essential machinery for respiration and metabolic homeostasis but is paradoxically among the most common targets of somatic mutations in the cancer genome, with truncating mutations in complex I genes being over-represented1 . While mtDNA mutations have been associ...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-08 | PXD044987 | Pride
Melanoma Cancer Complex i Mitochondrial dna 
ProteomicsMulti-omic profiling following loss of SWI/SNF reveals global changes in cohesin binding and sensitivity to cohesin perturbation
SWI/SNF is a family of multi-subunit chromatin remodelling complexes comprised of BAF, PBAF and ncBAF. These complexes have diverse roles in cellular processes including transcription, replication, and repair, and play an important role in maintaining genome stability, with over 20% of all cancers h...
ORGANISM(S): Homo sapiens (Human) 
2026-02-20 | PXD065273 | Pride
Cohesin Swi/snf 
Proteomicssdspage
exp 4: SDSPAGE
ORGANISM(S): Saccharomyces Cerevisiae 
2005-12-31 | PAe000158 | PeptideAtlas
TranscriptomicsRestoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle
In this study, we investigated signaling pathways in Skeletal muscle precursors that are altered with aging and age-related deficits in muscle regenerative potential. We performed fluorescence activated cell sorting (FACS) to obtain highly purified skeletal muscle satellite cells from young, middle-...
ORGANISM(S): Mus musculus 
2014-05-08 | E-GEOD-50821 | biostudies-arrayexpress
TranscriptomicsHigh-resolution copy number analysis of medulloblastoma
We used high-resolution SNP genotyping to identify regions of genomic gain and loss in the genome of 212 medulloblastomas, a malignant pediatric brain tumor. Focal amplifications of fifteen known oncogenes and focal deletions of twenty known tumor suppressor genes (TSG) were revealed, most not prev...
ORGANISM(S): Homo sapiens 
2010-04-06 | E-GEOD-14437 | biostudies-arrayexpress
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