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LC3-associated phagocytosis (LAP) is critical in host defense against invading pathogens, but the molecular mechanism for LAP activation is still unclear. Here, we find programmed cell death 6 (PDCD6) as a negative regulator of LAP. PDCD6 deficiency in mice and macrophages induces enhanced bacterici...
ORGANISM(S): Homo sapiens (Human) 
2024-10-18 | PXD056047 | Pride
Immunoprecipitation-MS analysis to identify AKR1B10 interacting proteins.
ORGANISM(S): Homo Sapiens 
2025-06-26 | PXD058680 |
This project try to provide Chinese yew dormant and germinating seed proteome
ORGANISM(S): Taxus Mairei 
2023-06-02 | PXD042641 |
The interplay between liver and bone metabolism remains largely uncharacterized. Here, we uncover a mechanism of liver-bone crosstalk regulated by hepatocyte SIRT2. We demonstrate that hepatocyte SIRT2 expression is increased in aged mice and elderly humans. Liver-specific SIRT2 deficiency inhibits ...
ORGANISM(S): Mus Musculus 
2023-03-27 | PXD041145 |
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