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ProteomicsSuccinylation profiles of brain injury after intracerebral hemorrhage
Protein posttranslational modifications (PTMs) has been shown to regulate biological processes of human diseases via expanding the genetic code and for regulating cellular pathophysiology, however, the system-wide changes at the PTMs levels in ICH brain remains little known. Given that succinylation...
ORGANISM(S): Mus musculus (Mouse) 
2021-10-29 | PXD025621 | Pride
Intracerebral hemorrhage  brain injury  succinylation 
ProteomicsDeep Succinylproteomics of Brain Tissues of Intracerebral Hemorrhage with inhibition of Toll-like receptor 4 signaling
The details of Toll-like receptor (TLR) 4 signaling affects protein succinylation in intracerebral hemorrhage (ICH) brains remains completely unclear. In this study, we constructed mice ICH models to investigate the changes in ICH-associated brain protein succinylation with the treatment of TLR4 ant...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-03 | PXD025622 | Pride
Intracerebral hemorrhage  brain injury  succinylation  toll-like receptor 4 
UnknownRegulation of Transcription Factor Yin Yang 1 by SET7/9-mediated Lysine Methylation.
Not available
S-EPMC4763200 | biostudies-literature
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
UnknownDecline of three farmland pest species in rapidly urbanizing landscapes.
Not available
S-EPMC8411231 | biostudies-literature
ProteomicsGlobal profiling of protein lactylation in Human hippocampi
Lysine lactylation (Kla) is a novel posttranslational modification, playing important roles in numerous biological processes, including transcription, metabolism, tumorigenesis and nervous system diseases. Using liquid chromatography-tandem mass spectrometry (LC-MS/MS), researchers have identified l...
ORGANISM(S): Homo Sapiens 
2024-03-08 | PXD050470 |
ProteomicsGut microbiota may underlie the predisposition of healthy individuals to COVID-19
The COVID-19 pandemic is spreading globally with high disparity in the susceptibility of the disease severity. Identification of the key underlying factors for this disparity is highly warranted. Here we describe constructing a proteomic risk score based on 20 blood proteomic biomarkers which predic...
ORGANISM(S): Homo Sapiens 
2020-06-09 | PXD019675 |
Proteomicsthe MS data involved in the article "Nuclear ACAT1 orchestrates natural killer cell-dependent antitumor immunity in colorectal cancer"
In this study we aim to explore the metabolic enzyme that affects NK cell function in colorectal cancer, and mainly focus on the mechanism how nuclear ACAT1（Mitochondrial acetyl-CoA acetyltransferase）promotes NK cell infiltration and activation
ORGANISM(S): Homo Sapiens 
2025-03-18 | PXD061959 |
UnknownObligate mutualism within a host drives the extreme specialization of a fig wasp genome.
Not available
S-EPMC4053974 | biostudies-literature
ProteomicsO-glycosylation in fruit development and ripening
O-glycosylation is a critical post-translational modification (PTM) regulating protein function, yet its role in plant transcription factors remains poorly understood.
ORGANISM(S): Solanum Lycopersicum 
2025-12-16 | PXD072030 |
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