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MetabolomicsFasudil may alleviate alcohol-induced astrocyte damage by modifying lipid metabolism, as determined by metabonomics analysis

Alcohol dependence is a chronic, relapsing encephalopathy characterized by compulsive craving for alcohol, loss of control over alcohol use, and the presence of negative emotions and physical discomfort when alcohol is unavailable. Harmful use of alcohol is one of the greatest risk factors for de...

2023-05-15 | MTBLS5071 | MetaboLights
MetabolomicsA Combined Proteomic and Metabolomic Strategy for Allergens Characterization in Natural and Fermented Brassica napus Bee Pollen

Bee pollen is consumed for its nutritional and pharmacological benefits, but it also contains hazardous allergens which has not been identified. Here, we identified 2 potential allergens, glutaredoxin and oleosin-B2, in Brassica napus (B. napus) bee pollen using mass spectrometr...

2022-03-23 | MTBLS3950 | MetaboLights
ProteomicsSolid-like condensation of MORF8 inhibits RNA editing under heat stress in Arabidopsis
Heat stress inhibits photosynthesis efficiency, thereby suppressing plant growth and crop yield. However, the mechanism underlying this inhibition is not fully understood. Here, we report that the multiple organellar RNA-editing factor 8 (MORF8) forms condensates with solid-like properties in chloro...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-03-07 | PXD061133 | Pride
Phase seperation Arabidopsis thaliana， rna editing 
MetabolomicsMechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis

Zhuyu pill (ZYP) is a traditional Chinese medicine prescription composed of two drugs, Coptis chinensis Franch. and Tetradium ruticarpum (A. Jussieu) T. G. Hartley, and is commonly used in the clinical treatment of diseases of the digestive system. However, the mechanism underly...

2022-11-02 | MTBLS4980 | MetaboLights
MetabolomicsFecal Metabolomics and Potential Biomarkers for Systemic Lupus Erythematosus
The role of metabolomics in autoimmune diseases has been a rapidly expanding area in researches over the last decade, while its pathophysiologic impact on systemic lupus erythematosus (SLE) remains poorly elucidated. In this study, we analyzed the metabolic profiling of fecal samples from SLE patien...
2020-01-30 | MTBLS916 | MetaboLights
TranscriptomicsRNase ZS1-mediated UbL40 mRNA decay controls thermo-sensitive genic male sterility in rice.
Male sterility is an important trait in hybrid crop breeding. Thermo-sensitive genic male sterility (TGMS) lines, which are male-sterile at restrictive (high) temperatures but convert to male-fertile at permissive (low) temperatures, have been widely utilized in two-line hybrid rice breeding3. Howev...
ORGANISM(S): Oryza sativa Indica Group 
2014-09-11 | E-GEOD-42314 | biostudies-arrayexpress
ProteomicsProteomics Analysis for Bee Pollen
To identify the potential proteins from bee pollen of Brassica by proteomics approach
ORGANISM(S): Brassica Napus 
2021-12-09 | PXD030273 |
ProteomicsQuantitative proteomics and phosphoproteomics of urinary extracellular vesicles define putative diagnostic biosignatures for Parkinson’s disease
Background: Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been recognized as genetic risk factors for Parkinson’s disease (PD). However, compared to cancer, fewer genetic mutations contribute to the cause of PD, propelling the search for protein biomarkers for early detection of th...
ORGANISM(S): Homo Sapiens 
2024-11-02 | PXD032175 | panorama
Proteomicsimmunoprecipitation-mass spectrometry related to rice stripe virus SP
immunoprecipitation-mass spectrometry related to rice stripe virus SP
ORGANISM(S): Oryza Sativa 
PXD063713 |
ProteomicsProteomic and phospho-proteomic raw data of Wilms tumor tissue and normal adjacent kidney tissue.
Proteomic and phospho-proteomic raw data of Wilms tumor tissue and normal adjacent kidney tissue from Wilms tumor patients.
ORGANISM(S): Homo Sapiens 
PXD063650 |
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