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ProteomicsThe pathogenic mechanism of ciprofloxacin in aortic aneurysm
The proteomics changes of VSMCs after CIP stimulation
ORGANISM(S): Homo Sapiens 
PXD037691 |
MetabolomicsComprehensive Untargeted Metabolomics Dataset of Saccharomyces cerevisiae Aging-Associated Mutants and Yeast–Host Interactions in Drosophila melanogaster

Aging is a complex biological process influenced by genetic factors, environmental conditions, and interactions between organisms and their associated microbes. The budding yeast Saccharomyces cerevisiae and the fruit fly Drosophila melanogaster provide complementary model systems for investigati...

2026-09-04 | MTBLS15555 | MetaboLights
ProteomicsAgeing- and AAA-associated Differentially Expressed Proteins Identified by Proteomic Analysis
We induced AAA in ApoE-/- mice of different ages (10 or 24 weeks) and obtained plasma samples. After the top 14 most abundant proteins were detected, the plasma was analyzed by a proteomic study using the data-dependent acquisition (DDA) technique.
ORGANISM(S): Mus Musculus 
2022-05-06 | PXD033725 |
ProteomicsUrinary proteomics identifying novel biomarkers for the diagnosis and phenotyping of carotid artery stenosis
We used the data-independent acquisition (DIA) technique to conduct a urinary proteomic study in patients with CAS and healthy controls.
ORGANISM(S): Homo Sapiens 
2021-06-04 | PXD026501 |
ProteomicsProteomic and phosphoproteomic profiling of original, Delta, or Omicron strain SARS-CoV-2-infected lung of rhesus macaque
The Omicron variant, mutated from the original SARS-CoV-2 strain, is still circulating worldwide. We performed LC-MS based proteome and phosphoproteome analysis using lung tissues separated from rhesus monkeys, which were infected with Omicron, the original virus or one of the VOCs, the Delta varian...
ORGANISM(S): Macaca Mulatta 
2023-12-12 | PXD047779 |
ProteomicsGlobal profiling of the proteome and acetylome in mice with abdominal aortic aneurysms
Abdominal Aortic Aneurysm (AAA) is a fatal vascular disease characterized by abnormal expansion of the arterial wall and a high risk of rupture. Current treatments for AAA primarily rely on surgical intervention, while effective pharmacological therapies have yet to be developed. The major bottlenec...
ORGANISM(S): Mus Musculus 
2025-02-17 | PXD060895 |
ProteomicsSmall intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning
Sepsis is a severe global health issue with high mortality rates, and sepsis-associated encephalopathy (SAE) further exacerbates this risk. While recent studies have shown the migration of gut immune cells to the lungs after sepsis, their impact on the central nervous system remains unclear. Our res...
ORGANISM(S): Mus Musculus 
2024-10-28 | PXD057241 |
ProteomicsA comprehensive proteome and phosphoproteome atlas across nine organs of the Chinese hamster
We present the first comprehensive proteomic and phosphoproteomic atlas of nine major organs of the Chinese hamster (Cricetulus griseus). A total of 14,219 proteins, 11,828 phosphorylated proteins, and 47,122 phosphorylation sites were identified, revealing distinct inter-organ molecular features.
ORGANISM(S): Cricetulus Griseus 
PXD069241 |
ProteomicsProteomic analysis of 442 clinical plasma samples from healthy donors and COVID-19 covalescent patients
In this study, we collected plasma samples from 22 healthy controls (HC group), 43 hospitalized patients (HO group), 196 convalescent patients 6 months after COVID-19 infection (first follow-up, F1 group), and 181 convalescent patients 12 months after COVID-19 infection (second follow-up, F2 group)....
ORGANISM(S): Homo Sapiens 
PXD054533 |
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