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UnknownThe Long Noncoding RNA NEAT1 Promotes Sarcoma Metastasis by Regulating RNA Splicing Pathways.
Not available
S-EPMC7541426 | biostudies-literature
UnknownMutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation.
Not available
S-EPMC10592452 | biostudies-literature
TranscriptomicsProfiling Side Population Cells in Malignant Fibrous Histiocytoma
We are currently studying the mechanisms that confer tumour initiating potential upon SP, and as part of this work, we undertook gene profiling studies comparing expression between SP and non-SP cells, initially focusing on the most common soft tissue sarcoma, malignant fibrous histiocytoma (or MFH)...
ORGANISM(S): Homo sapiens 
2012-01-17 | E-GEOD-32375 | biostudies-arrayexpress
TranscriptomicsNovel Properties of Side Population cells in Soft-tissue Sarcoma, and How They May Be Targeted to Develop Potential Therapies
Tumours contain heterogeneous cell populations. A population enriched in tumour-initiating potential has been identified in soft-tissue sarcoma (STS) by the isolation of side population (SP) cells. In this study, we compared the gene expression profiles of SP and non-SP cells in STS and identified H...
ORGANISM(S): Homo sapiens 
2012-01-17 | E-GEOD-24199 | biostudies-arrayexpress
GenomicsH3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation [Ring1b_ChIP]
The goal of this study is to understand the genome-wide alterations in chromatin landscape induced by a histone mutation (H3.3K36M) derived from chondroblastomas Examination of genome-wide Ring1b distribution in cells expressing H3.3WT and H3.3K36M.
ORGANISM(S): Mus musculus 
2016-05-13 | E-GEOD-69286 | biostudies-arrayexpress
GenomicsH3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation [Cbx2_ChIP]
The goal of this study is to understand the genome-wide alterations in chromatin landscape induced by a histone mutation (H3.3K36M) derived from chondroblastomas Examination of genome-wide Cbx2 distribution in cells expressing H3.3WT and H3.3K36M.
ORGANISM(S): Mus musculus 
2016-05-13 | E-GEOD-75856 | biostudies-arrayexpress
TranscriptomicsH3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation [Ring1a-1b_RNASeq]
The goal of this study is to understand the genome-wide alterations in chromatin landscapy induced by a histone mutation (H3.3 K36M) derived from chondroblastomas Examination of the transcriptome changes of Ring1a and Ring1b knockdown in mouse mesenchymal progenitor cells
ORGANISM(S): Mus musculus 
2016-05-13 | E-GEOD-75854 | biostudies-arrayexpress
UnknownPrognostic microRNAs modulate the RHO adhesion pathway: A potential therapeutic target in undifferentiated pleomorphic sarcomas.
Not available
S-EPMC4770761 | biostudies-literature
TranscriptomicsH3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2016-05-13 | E-GEOD-69291 | biostudies-arrayexpress
ProteomicsImmuno-Transcriptomic Profiling Identifies Actionable Alterations in Pediatric Solid Malignancies
Immuno-Transcriptomic Profiling Identifies Actionable Alterations in Pediatric Solid Malignancies
ORGANISM(S): Homo sapiens (Human) 
2021-12-07 | PXD017130 | Pride
Immunology  transcriptome  pediatric  malignancies 
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