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Genomic comparison of more and less invasive strains of Neisseria meningitidis
ORGANISM(S): Neisseria meningitidis 
Novel functional coding sequences (altORFs) are camouflaged within annotated ones (CDS) in a different reading frame. We discovered an altORF nested in the FUS CDS encoding a conserved 170 amino acid protein, altFUS. AltFUS is endogenously expressed in human tissues, notably in the motor cortex and ...
ORGANISM(S): Homo sapiens (Human) 
2020-10-12 | PXD021320 | Pride
Rationale: Chronic obstructive pulmonary disease (COPD) is a prevalent respiratory disease lacking disease modifying treatment. The role of CXCL12/CXCR4 axis has been demonstrated in acute exacerbation of COPD. The interest of study early COPD has been recently pointed out. Objectives: To study the...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-12 | PXD040105 | Pride
Rehabilitation using cryotherapy has widely been used in inflammatory diseases to relieve pain and decrease the disease activity. The aim of this study was to explore the metabolite changes in inflammatory knee-joint synovial fluids following local cryotherapy treatment (ice or cold CO2). We used pr...
2020-11-10 | MTBLS1894 | MetaboLights
BACKGROUND & AIMS: C/EBPbeta is involved in numerous process as carcinogenesis but its role is still not clear due to the existence of an active form (LAP) and an inhibitory form (LIP) of this transcription factor. The main goals of the present research were (i) the identification of genes inversely...
ORGANISM(S): Homo sapiens 
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