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MetabolomicsSacha inchi oil alleviates gut microbiota dysbiosis and improves hepatic lipid dysmetabolism in high-fat diet-fed rats
Dietary ω-3 polyunsaturated fatty acids (PUFAs) are beneficial for humans against the development of hyperlipidaemia, but the underlying mechanisms are still poorly understood. Here, we demonstrated that oral consumption of sacha inchi oil, which is rich in α-linolenic acid, alleviated dyslipidemia,...
2022-02-21 | MTBLS1225 | MetaboLights
MetabolomicsSupplementation of Bacillus sp. DU-106 reduces hypercholesterolemia and ameliorates gut dysbiosis in high-fat diet rats

Gut microbiota modulation by a probiotic is a novel therapy for hypercholesterolemia mitigation. This study initially investigated the potential hypocholesterolemic effect of Bacillus sp. DU-106 in hypercholesterolemic rats and explored its potential relation with gut microbiota. Sprague-Dawley r...

2021-04-08 | MTBLS1168 | MetaboLights
UnknownComparative Study of the Chemical Constituents and Bioactivities of the Extracts from Fruits, Leaves and Root Barks of Lycium barbarum.
Not available
S-EPMC6514792 | biostudies-literature
UnknownCandida auris-associated hospitalizations and outbreaks, China, 2018-2023.
Not available
S-EPMC10802803 | biostudies-literature
UnknownFirst case of fungemia caused by a rare and pan-echinocandin resistant yeast <i>Sporopachydermia lactativora</i> in China.
Not available
S-EPMC12096653 | biostudies-literature
ProteomicsLabel-free proteomics of two bacterial strains grown on hydrocarbon
Two bacterial strains isolated from Chinese oilfield, Dietzia sp. DQ12-45-1b and P. stutzeri SLG510A3-8, were found having synergistic effect on hydrocarbon biodegradation. To investigate the synergy mechanism between the two strains, they were cultivated separately or individually in a two-chamber ...
ORGANISM(S): Dietzia Sp. Dq12-45-1b Pseudomonas Stutzeri 
2019-12-15 | PXD016754 |
TranscriptomicsEffect of BMP4 and noggin on gene expression in murine R1 ES cells
To confirm that the SMAD1/5- and SMAD4-associated genes are direct transcriptional regulators in mESCs in response to BMP, we treated undifferentiated R1 ES cells with BMP4 or with the BMP4 antagonist noggin, which can inhibit BMP signaling effectively for 4 h. Undifferentiated R1 ES cells were trea...
ORGANISM(S): Mus musculus 
2010-03-07 | E-GEOD-20527 | biostudies-arrayexpress
ProteomicsCDH11 regulates presynaptic vesicle trafficking and neuronal activity in autism-related brain circuit
The molecular etiology of numerous risk genes for autism spectrum disorder (ASD), including CDH11, remains elusive. We investigated the role of CDH11 in the development of ASD-related behaviors using gene-deficient mice. CDH11 is enriched at synapses in glutamatergic neurons of the anterior cingulat...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-08 | PXD055834 | Pride
Synaptic adhesion Asd Neuronal activity Proteomics Brain circuit Self-grooming Cdh11 Acc 
ProteomicsCDH11 regulates presynaptic vesicle trafficking and neuronal activity in autism-related brain circuit
The molecular etiology of numerous risk genes for autism spectrum disorder (ASD), including CDH11, remains elusive. We investigated the role of CDH11 in the development of ASD-related behaviors using gene-deficient mice. CDH11 is enriched at synapses in glutamatergic neurons of the anterior cingulat...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-08 | PXD056074 | Pride
Synaptic adhesion Asd Neuronal activity Proteomics Brain circuit Self-grooming Cdh11 Acc 
ProteomicsCDH11 regulates presynaptic vesicle trafficking and neuronal activity in autism-related brain circuit
The molecular etiology of numerous risk genes for autism spectrum disorder (ASD), including CDH11, remains elusive. We investigated the role of CDH11 in the development of ASD-related behaviors using gene-deficient mice. CDH11 is enriched at synapses in glutamatergic neurons of the anterior cingulat...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-08 | PXD056411 | Pride
Synaptic adhesion Asd Neuronal activity Proteomics Brain circuit Self-grooming Cdh11 Acc 
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