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ProteomicsQuantitative proteomic analysis of Ricinus communis during early seed imbibition provided novel insights into cold stress response
Early planting is one of the strategies used to increase grain yield in temperate regions. However, poor cold tolerance in castor inhibits seed germination, resulting in lower seedling emergence and biomass. To date, proteomics studies have identified diverse proteins associated with germinating or ...
ORGANISM(S): Ricinus Communis 
2018-06-05 | PXD010043 |
TranscriptomicsAn optimized RNA amplification method for prokaryotic expression profiling analysis
Conventional prokaryotic RNA labeling method usually requires large amounts of starting materials and tends to generate high background signals. Recently, two novel methods based on amplification systems were introduced. Here, we compared three alternative strategies: direct labeling method, ployade...
ORGANISM(S): Escherichia coli 
2010-05-15 | E-GEOD-17074 | biostudies-arrayexpress
UnknownAntioxidant and Anti-Fatigue Constituents of Okra.
Not available
S-EPMC4632455 | biostudies-literature
MetabolomicsClinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats.

OBJECTIVE: To observe the clinical efficacy and safety of Yiqi Yangxue formula (YQYXF) on knee osteoarthritis (KOA), and to explore the underlying therapeutic mechanism of YQYXF through endogenous differential metabolites and their related metabolic pathways.

METHOD...

2024-03-25 | MTBLS5667 | MetaboLights
ProteomicsMST4 promotes MRC2 activity to drive osteosarcoma proliferation
Osteosarcoma is one of the most common types of orthopedic malignancies with an accelerated disease progression and poor prognosis.The purpose of this study was to further investigate the function of Serine/threonine protein kinase 4(MST4) in osteosarcoma and its underlying mechanisms. The expressio...
ORGANISM(S): Homo sapiens (Human) 
2026-10-26 | PXD034216 | Pride
Mrc2 Mst4 Osteosarcoma proliferation 
ProteomicsIdentification of a biomarker to predict doxorubicin/cisplatin chemotherapy efficacy for osteosarcoma patients by 4D data-independent acquisition (DIA) mass spectrometry with parallel reaction monitoring (PRM) verification
We analyzed the differentially expressed proteins in 37 resected tissue samples from osteosarcoma patients using paraffin- embedded specimens and 4D data-independent acquisition (DIA) quantitative mass spectrometry to investigate biomarkers for predicting the efficacy of doxorubicin/cisplatin chemot...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD051097 | Pride
Osteosarcoma  doxorubicin/cisplatin chemotherapy efficacy  data-independent acquisition (dia) mass spectrometry with parallel reaction monitoring (prm)  ctsg  neutrophil extracellular traps (nets) 
ProteomicsMyo19 Interacting Proteins IP-MS
This project is aimed to detect the interacting proteins of mitochondria-tageting actin motor Myo19.
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD033198 | Pride
Myo19 ip-ms 
GenomicsSingle Cell Sequencing Identifies Key Epigenetic Regulators in Nuclear Transfer Mediated Reprogramming [ChIP-seq]
Differentiated cell can be reprogrammed into totipotent embryo through somatic cell nuclear transfer (SCNT). However, this process is highly inefficient and most cloned embryos arrest at certain developmental stages. Through single cell sequencing combined with embryo biopsy, here we generate a glob...
ORGANISM(S): Mus musculus 
2016-05-17 | E-GEOD-70606 | biostudies-arrayexpress
Proteomics,Multiomicsembryo_proteome
We collected over 8000 mouse embryos of each developmental stage (zygote, 2-cell, 4-cell, 8-cell, morula, blastocyst) and performed tandem mass tag (TMT)-based quantitative mass spectrometry and identified nearly 5000 proteins for each stage. In-depth analysis indicates that protein expression profi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2015-12-10 | MSV000079417 | MassIVE
TranscriptomicsIFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq]
IFN-g primes macrophages for enhanced inflammatory activation by TLRs and microbial killing, but little is known about the regulation of cell metabolism or mRNA translation during priming. We found that IFN-g regulates macrophage metabolism and translation in an integrated manner by targeting mTORC1...
ORGANISM(S): Homo sapiens 
2015-06-29 | E-GEOD-66809 | biostudies-arrayexpress
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