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UnknownEndoderm convergence controls subduction of the myocardial precursors during heart-tube formation.
Not available
S-EPMC10682956 | biostudies-literature
ProteomicsNLRP6 controls PTEN stability by promoting autophagic degradation of p85α to drive tumorigenesis
To identify NLRP6-associated proteins in living cells, we applied an APEX2-based labelling method combined with mass spectrometry. In brief, APEX2 was genetically fused to NLRP6. In the presence of hydrogen peroxide, APEX2 catalysed biotin-phenol to become a biotin-phenol radical that covalently bou...
ORGANISM(S): Homo sapiens (Human) 
2023-07-02 | PXD037460 | Pride
Human Lc-ms/ms 
UnknownCharacterization of the Human Adipocyte Proteome and Reproducibility of Protein Abundance by One-Dimensional Gel Electrophoresis and HPLC-ESI-MS/MS.
Not available
S-EPMC2935302 | biostudies-literature
UnknownCharacterizing Disease Severity Through Surgical Recurrence Rates in Idiopathic Subglottic Stenosis.
Not available
S-EPMC12475557 | biostudies-literature
UnknownA self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models.
Not available
S-EPMC8721936 | biostudies-literature
ProteomicsPlasma proteome profiling combined with clinical and genetic features reveals pathophysiological characteristics of β-thalassemia
The phenotype of β-thalassemia underlies multigene interactions, making clinical stratification complicated. An increasing number of genetic modifiers affecting the disease severity have been identified, but are still unable to meet the demand of precision diagnosis. Here, we systematically conducte...
ORGANISM(S): Homo Sapiens 
2022-03-10 | PXD032179 |
ProteomicsNociceptive neurons inhibit neutrophil extracellular trap formation via MLKL-licensed histone release
This data set contains the raw data of proteinomic analysis of dorsal root ganglions (DRGs) in WT and MLKL-KO mice under basal condition and after CFA treatment, and MLKL-based IP-MS analysis of WT DRGs under basal condition and after CFA treatment.
ORGANISM(S): Mus Musculus 
2026-04-16 | PXD077273 |
Proteomicsβ-thalassemia plasma EVs proteomics
Here, we performed plasma extracellular vesicles (EVs) proteomics on 20 β-thalassemia major (TM) patients, 20 intermedia (TI) patients, and 20 healthy controls to explore the subgroup characteristics and the potential biomarkers. The proteome of paired plasma was analyzed in parallel to compare the ...
ORGANISM(S): Homo Sapiens 
2022-06-15 | PXD034548 |
ProteomicsDisrupting metformin adaptation of hepatocellular carcinoma by targeting TOMM34/ATP5B axis
As a well-known anti-diabetic drug, metformin has been repurposed for cancer treatment, but drug resistance and tumor metastasis observed recently have challenged its further application. Here, we found that long-term metformin exposure led to metabolic adaptation of HCC cells, which was characteriz...
ORGANISM(S): Homo Sapiens 
2022-07-14 | PXD035365 |
UnknownlncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.
Not available
S-EPMC6143179 | biostudies-literature
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