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MetabolomicsMetabolomic approaches to dissect dysregulated metabolism in the progression of pre-diabetes to T2DM

Most of pre-diabetes were eventually progress to diabetes, thereby profiling of prediabetic metabolic disorders may be an effective targeted preventive measure. We aimed to elucidate internal motivation of the progression of pre-diabetes to type 2 diabetes mellitus (T2DM) from a metabolic perspec...

2024-04-29 | MTBLS8644 | MetaboLights
UnknownChristensenella regulated by Huang-Qi-Ling-Hua-San is a key factor by which to improve type 2 diabetes.
Not available
S-EPMC9597676 | biostudies-literature
UnknownDeciphering the Potential Pharmaceutical Mechanism of GUI-ZHI-FU-LING-WAN on Systemic Sclerosis based on Systems Biology Approaches.
Not available
S-EPMC6344516 | biostudies-literature
ProteomicsAnalysis of protein expression changes in patients with prediabetes using high-throughput proteomics
Objective: This study aimed to explore the mechanisms of early-onset T2DM by analyzing proteomic changes at different stages of glucose metabolism. Methods: A total of 40 individuals undergoing routine physical health examinations between December 2016 and April 2017 were enrolled. Subjects were di...
ORGANISM(S): Homo Sapiens 
2022-10-19 | PXD035367 |
UnknownThe complete chloroplast genome sequence of Oxalis corniculata (L.).
Not available
S-EPMC8043542 | biostudies-literature
MetabolomicsMetabolome analysis reveal key regulatory pathways of feed conversion efficiency of oriental river prawn Macrobrachium nipponense

A total of 445 and 247 differently expressed metabolites (DEMs) were identified in the hepatopancreas and muscle. In addition, 11 KEGG pathways, which mainly include lysine biosynthesis, lysine degradation, aminoacyl-tRNA biosynthesis and purine metabolism, were sign...

2023-02-28 | MTBLS6663 | MetaboLights
UnknownRapid synthesis of cesium lead halide perovskite nanocrystals by l-lysine assisted solid-phase reaction at room temperature.
Not available
S-EPMC9056784 | biostudies-literature
Proteomicscentipedegrass tiller bud and internode proteome
This study investigate the differentially expressed proteins in tiller bud and internode between a high tillering mutant and wild type.
ORGANISM(S): Eremochloa ophiuroides 
2024-06-16 | PXD047559 | Pride
Centipedegrass Tiller bud Proteome 
UnknownPSORI-CM02 Formula Increases CD4+ Foxp3+ Regulatory T Cell Frequency and Ameliorates Imiquimod-Induced Psoriasis in Mice.
Not available
S-EPMC5766646 | biostudies-literature
ProteomicsActivation of hypothalaActivation of hypothalamic-enhanced adult-born neurons is sufficient to restore cognitive and noncognitive function in Alzheimer's diseasemic-enhanced adult-born neurons is sufficient to restore cognitive and noncognitive function in Alzheimer's diseaseActivation of hypothalamic-enhanced adult-born neurons is sufficient to restore cognitive and noncognitive function in Alzheimer's disease
Patients with Alzheimer’s disease (AD) exhibit progressive memory loss, depression, and anxiety, accompanied by impaired adult hippocampal neurogenesis (AHN). Whether modulating AHN is sufficient to improve these cognitive and noncognitive symptoms in AD remains elusive. Here we report that chronic ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-08 | PXD034176 | Pride
Mouse Hippocampus Lc-ms Phosphoproteom 
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