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MetabolomicsMetabolomic approaches to dissect dysregulated metabolism in the progression of pre-diabetes to T2DM

Most of pre-diabetes were eventually progress to diabetes, thereby profiling of prediabetic metabolic disorders may be an effective targeted preventive measure. We aimed to elucidate internal motivation of the progression of pre-diabetes to type 2 diabetes mellitus (T2DM) from a metabolic perspec...

2024-04-29 | MTBLS8644 | MetaboLights
ProteomicsHuman serum samples proteomic analysis
Vitamin D deficiency affected the abnormal protein expression, resulting in the abnormal activation of complement system.
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD036152 | Pride
Serum Proteomic Label-free Human 
ProteomicsAnalysis of protein expression changes in patients with prediabetes using high-throughput proteomics
Objective: This study aimed to explore the mechanisms of early-onset T2DM by analyzing proteomic changes at different stages of glucose metabolism. Methods: A total of 40 individuals undergoing routine physical health examinations between December 2016 and April 2017 were enrolled. Subjects were di...
ORGANISM(S): Homo Sapiens 
2022-10-19 | PXD035367 |
ProteomicsProteomics reveals that immunoglobulin abnormalities and immune dysregulation in patients with post–COVID-19 condition
Vitamin D (VD) has a coordinated immune function. Decreased VD levels are closely related to the occurrence of post-COVID-19 Conditions (PCC), but the specific mechanism is still unclear. Methods: We collected 50 PCC patient serum samples and divided them into three groups by different VD levels: VD...
ORGANISM(S): Homo Sapiens 
2025-11-27 | PXD059686 |
UnknownSex Differences in Genetic Associations With Longevity.
Not available
S-EPMC6173523 | biostudies-literature
TranscriptomicsIdentification of copper (Cu) stress-responsive grapevine microRNAs and their target genes by high-throughput sequencing
Background: MicroRNAs (miRNAs) are a class of single-stranded non-coding small RNAs (sRNAs) that are 20-24 nucleotides (nt) in length. Extensive studies have indicated that miRNAs play important roles in plant growth, development, and stress responses. With more copper (Cu) and copper-containing com...
ORGANISM(S): Vitis labrusca x Vitis vinifera 
2016-02-20 | E-GEOD-78133 | biostudies-arrayexpress
ProteomicsHuman bladder cancer LC MS/MS
Urine is an ideal material to study and examine the bladder cancer (BCa) biomarkers, whereas exploration to the corresponding protein candidates is confronting technique challenges. Herein, we proposed a comprehensive strategy of searching the urine proteins related to BCa. The strategy consists of ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080696 | MassIVE
UnknownEfficacy and Safety of Ginkgo Diterpene Lactone Meglumine in Acute Ischemic Stroke: A Randomized Clinical Trial.
Not available
S-EPMC10425831 | biostudies-literature
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